GGA1 and CCDC91

Number of citations of the paper that reports this interaction (PubMedID 12808037)
24

Data Source:
HPRD (in vivo, in vitro)

		GGA1	CCDC91
Description		golgi associated, gamma adaptin ear containing, ARF binding protein 1	coiled-coil domain containing 91
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GO Annotations	Cellular Component	Nucleoplasm Early Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Nucleoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane
	Molecular Function	Molecular_function Protein Binding ADP-ribosylation Factor Binding	Identical Protein Binding
	Biological Process	Intracellular Protein Transport Protein Localization Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Cellular Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Toxin Transport Protein Localization To Ciliary Membrane	Protein Transport Golgi To Lysosome Transport
Pathways		TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Health literacy ( 31250787)	Adverse response to drug ( 30420678) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Bone ultrasound measurement (velocity of sound) ( 28472463) Breast size ( 27182965) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 23563607 31562340) Hip circumference adjusted for BMI ( 25673412) Lumbar spine bone mineral density (trabecular) ( 27476799) Lung function (FEV1) ( 28166213 26635082) Lung function (FVC) ( 28166213 26635082 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Narrowest width of the femoral neck ( 30888730) Obesity-related traits ( 23251661) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis of the hand ( 28855172) Peak expiratory flow ( 30804560) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes		38 interacting genes: ADRA2B AFTPH AP1AR APP ARF1 ARF3 ARF5 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CLINT1 CLTC CSNK2A1 DTNB EGFR F8 GGA2 GGA3 IGF2R LRP3 M6PR RABEP1 RABGEF1 RNF11 RPS27A SCARB1 SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TSG101 UBC VPS18	6 interacting genes: ECT2 EWSR1 GGA1 GGA2 SYNRG TESC
Entrez ID		26088	55297
HPRD ID		12078	16905
Ensembl ID		ENSG00000100083	ENSG00000123106
Uniprot IDs		Q9UJY5	A0A024RAW6 Q05D28 Q7Z6B0
PDB IDs		1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W	1OM9
Enriched GO Terms of Interacting Partners?
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