CLIC4 and DNM1

Number of citations of the paper that reports this interaction (PubMedID 11563969)
29

Data Source:
HPRD (in vitro)

		CLIC4	DNM1
Description		chloride intracellular channel 4	dynamin 1
Image
GO Annotations	Cellular Component	Intracellular Cell Nucleus Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Microvillus Cell-cell Junction Cell Surface Actin Cytoskeleton Microtubule Cytoskeleton Nuclear Matrix Midbody Cytoplasmic Vesicle Membrane Chloride Channel Complex Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Exosome	Photoreceptor Inner Segment Nucleoplasm Cytoplasm Golgi Apparatus Microtubule Plasma Membrane Synaptic Vesicle Postsynaptic Density Microtubule Cytoskeleton Membrane Membrane Coat Axon Cytoplasmic Vesicle Mitochondrial Membrane Varicosity Dendritic Spine Dendritic Spine Head Synapse Postsynaptic Membrane Extracellular Exosome Photoreceptor Ribbon Synapse Presynaptic Endocytic Zone Membrane Postsynaptic Endocytic Zone Membrane Glutamatergic Synapse
	Molecular Function	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding	RNA Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Protein C-terminus Binding SH3 Domain Binding Protein Kinase Binding D2 Dopamine Receptor Binding Identical Protein Binding Protein-containing Complex Binding Nitric-oxide Synthase Binding
	Biological Process	Angiogenesis Endothelial Cell Morphogenesis Chloride Transport Vacuolar Acidification Fertilization Cell Differentiation Keratinocyte Differentiation Negative Regulation Of Cell Migration Regulation Of Ion Transmembrane Transport Establishment Or Maintenance Of Apical/basal Cell Polarity Multicellular Organism Growth Branching Morphogenesis Of An Epithelial Tube Regulation Of Cytoskeleton Organization Retina Vasculature Morphogenesis In Camera-type Eye Cellular Response To Calcium Ion Chloride Transmembrane Transport	Mitochondrial Fission G Protein-coupled Receptor Internalization Endocytosis Receptor-mediated Endocytosis Endosome Organization Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Ephrin Receptor Signaling Pathway Organelle Fission Regulation Of Synapse Structure Or Activity Modulation Of Chemical Synaptic Transmission Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization Positive Regulation Of Synaptic Vesicle Endocytosis Toxin Transport Response To Amyloid-beta
Pathways			Toll Like Receptor 4 (TLR4) Cascade Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Recycling pathway of L1 Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Height ( 20881960) Male-pattern baldness ( 28196072) Systolic blood pressure ( 29208002)	Attention deficit hyperactivity disorder ( 18839057) Body mass index ( 26426971) Coenzyme Q10 levels ( 27149984)
Interacting Genes		5 interacting genes: ACTB DNM1 HSP90AB1 REL YWHAZ	46 interacting genes: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CEP126 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GRB2 GRIN1 GRIN2D ITSN1 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP RACK1 SH3GL1 SH3GL2 SH3GL3 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I
Entrez ID		25932	1759
HPRD ID		05943	03851
Ensembl ID		ENSG00000169504	ENSG00000106976
Uniprot IDs		Q6FIC5 Q9Y696	B4DK06 B7ZAC0 Q05193
PDB IDs		2AHE 2D2Z 3OQS	1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS 4UUD 4UUK 5D3Q 6DLU 6DLV
Enriched GO Terms of Interacting Partners?
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