NIPBL and HINFP

Number of citations of the paper that reports this interaction (PubMedID 17577209)
10

Data Source:
BioGRID (two hybrid)

		NIPBL	HINFP
Description		NIPBL cohesin loading factor	histone H4 transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromatin Nuclear Chromatin Nucleus Nucleoplasm Cytosol Integrator Complex SMC Loading Complex Intracellular Membrane-bounded Organelle Extracellular Exosome Scc2-Scc4 Cohesin Loading Complex	Nucleus Nucleoplasm Nucleolus Cajal Body
	Molecular Function	Chromatin Binding Protein Binding Protein C-terminus Binding Mediator Complex Binding Histone Deacetylase Binding Protein N-terminus Binding Chromo Shadow Domain Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Enzyme Binding Histone Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Heart Morphogenesis Outflow Tract Morphogenesis Double-strand Break Repair Cellular Response To DNA Damage Stimulus Mitotic Sister Chromatid Cohesion Mitotic Chromosome Condensation Brain Development Heart Development Sensory Perception Of Sound Stem Cell Population Maintenance Positive Regulation Of Histone Deacetylation Establishment Of Mitotic Sister Chromatid Cohesion Maintenance Of Mitotic Sister Chromatid Cohesion Cellular Protein Localization Embryonic Forelimb Morphogenesis Forelimb Morphogenesis External Genitalia Morphogenesis Positive Regulation Of Multicellular Organism Growth Ear Morphogenesis Regulation Of Hair Cycle Fat Cell Differentiation Positive Regulation Of Ossification Negative Regulation Of Transcription, DNA-templated Regulation Of Embryonic Development Embryonic Digestive Tract Morphogenesis Developmental Growth Eye Morphogenesis Regulation Of Developmental Growth Embryonic Viscerocranium Morphogenesis Cognition Face Morphogenesis Gall Bladder Development Uterus Morphogenesis RDNA Condensation Establishment Of Protein Localization To Chromatin Cellular Response To X-ray Transcriptional Activation By Promoter-enhancer Looping Cohesin Loading Positive Regulation Of Mitotic Cohesin Loading Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Positive Regulation Of Neuron Migration	DNA Damage Checkpoint G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		Cohesin Loading onto Chromatin
Drugs
Diseases		Cornelia de Lange syndrome (CdLS)
GWAS		Height ( 28552196 25282103 31562340) Obesity-related traits ( 23251661) Weight ( 28552196)
Interacting Genes		6 interacting genes: CBX5 CDK6 DBN1 HINFP PRSS23 SP100	28 interacting genes: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 IHO1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TP53 TRA2B TRAF2 TRIM39 TRIM44 TTF2 U2AF1 ZNHIT1
Entrez ID		25836	25988
HPRD ID		10560	07387
Ensembl ID		ENSG00000164190	ENSG00000172273
Uniprot IDs		A0A590UJS4 Q6KC79	A0A024R3F5 Q9BQA5
PDB IDs
Enriched GO Terms of Interacting Partners?
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