TXN2 and PPCDC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TXN2	PPCDC
Description		thioredoxin 2	phosphopantothenoylcysteine decarboxylase
Image
GO Annotations	Cellular Component	Cell Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Cytosol
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding	Phosphopantothenoylcysteine Decarboxylase Activity Protein Binding Identical Protein Binding
	Biological Process	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process	Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	Coenzyme A biosynthesis
Drugs			Riboflavin Monophosphate Pantothenoylaminoethenethiol
Diseases
GWAS			Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707) Heel bone mineral density ( 30598549) Systemic lupus erythematosus ( 26502338)
Interacting Genes		35 interacting genes: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 SUN2 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14	9 interacting genes: CENPT DBI FOXR1 NTAQ1 PPIG PSMA1 SREK1IP1 TXN2 ZNF232
Entrez ID		25828	60490
HPRD ID		07161	14377
Ensembl ID		ENSG00000100348	ENSG00000138621
Uniprot IDs		B4DX69 Q99757	H3BQB0 H3BRQ0 H3BSE3 H3BU63 Q96CD2
PDB IDs		1UVZ 1W4V 1W89	1QZU
Enriched GO Terms of Interacting Partners?
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