GAA and PARD3B

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		GAA	PARD3B
Description		glucosidase alpha, acid	par-3 family cell polarity regulator beta
Image			No pdb structure
GO Annotations	Cellular Component	Cell Lysosome Lysosomal Membrane Plasma Membrane Membrane Azurophil Granule Membrane Lysosomal Lumen Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Cell Cytoplasm Adherens Junction Bicellular Tight Junction Cell Cortex Endomembrane System Apical Plasma Membrane Cell Junction Protein-containing Complex Apical Junction Complex
	Molecular Function	Alpha-1,4-glucosidase Activity Carbohydrate Binding Maltose Alpha-glucosidase Activity	Protein Binding Phosphatidylinositol Binding
	Biological Process	Maltose Metabolic Process Regulation Of The Force Of Heart Contraction Diaphragm Contraction Heart Morphogenesis Glycogen Catabolic Process Sucrose Metabolic Process Glucose Metabolic Process Lysosome Organization Locomotory Behavior Tissue Development Vacuolar Sequestering Neutrophil Degranulation Muscle Cell Cellular Homeostasis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance Cardiac Muscle Contraction	Microtubule Cytoskeleton Organization Cell Cycle Cell Adhesion Protein Localization Establishment Of Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Division Establishment Of Centrosome Localization
Pathways		Glycogen storage disease type II (GAA) Neutrophil degranulation Glycogen breakdown (glycogenolysis)
Drugs		Acarbose Miglitol AT2220
Diseases		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Blood protein levels ( 30072576)	AIDS progression ( 21502085) Aluminium levels ( 26025379) Attention deficit hyperactivity disorder ( 30563984) Autism ( 22843504) Body mass index ( 28892062) Craniofacial microsomia ( 26853712) Diisocyanate-induced asthma ( 25918132) General risk tolerance (MTAG) ( 30643258) Hip circumference adjusted for BMI ( 28552196) Hippocampal volume ( 25625606) Idiopathic dilated cardiomyopathy ( 29495422) Intracranial aneurysm ( 29531279) Intraocular pressure ( 29617998 29785010 31959993 30054594) Knee osteoarthritis ( 18471798) Post bronchodilator FEV1/FVC ratio ( 26634245) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		9 interacting genes: CPEB2 DYNC1LI2 EP300 HIVEP1 NCF1 NUMBL PARD3B SH3GLB2 STAT2	9 interacting genes: CASK GAA INSC MARK2 PARD6B RBM5 RPS6KA1 YWHAE YWHAG
Entrez ID		2548	117583
HPRD ID		06006	09795
Ensembl ID		ENSG00000171298	ENSG00000116117
Uniprot IDs		P10253	Q8TEW8
PDB IDs		5KZW 5KZX 5NN3 5NN4 5NN5 5NN6 5NN8
Enriched GO Terms of Interacting Partners?
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