PARD3B and GAA

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		PARD3B	GAA
Description		par-3 family cell polarity regulator beta	glucosidase alpha, acid
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Adherens Junction Bicellular Tight Junction Cell Cortex Endomembrane System Apical Plasma Membrane Cell Junction Protein-containing Complex Apical Junction Complex	Cell Lysosome Lysosomal Membrane Plasma Membrane Membrane Azurophil Granule Membrane Lysosomal Lumen Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Phosphatidylinositol Binding	Alpha-1,4-glucosidase Activity Carbohydrate Binding Maltose Alpha-glucosidase Activity
	Biological Process	Microtubule Cytoskeleton Organization Cell Cycle Cell Adhesion Protein Localization Establishment Of Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Division Establishment Of Centrosome Localization	Maltose Metabolic Process Regulation Of The Force Of Heart Contraction Diaphragm Contraction Heart Morphogenesis Glycogen Catabolic Process Sucrose Metabolic Process Glucose Metabolic Process Lysosome Organization Locomotory Behavior Tissue Development Vacuolar Sequestering Neutrophil Degranulation Muscle Cell Cellular Homeostasis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance Cardiac Muscle Contraction
Pathways			Glycogen storage disease type II (GAA) Neutrophil degranulation Glycogen breakdown (glycogenolysis)
Drugs			Acarbose Miglitol AT2220
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		AIDS progression ( 21502085) Aluminium levels ( 26025379) Attention deficit hyperactivity disorder ( 30563984) Autism ( 22843504) Body mass index ( 28892062) Craniofacial microsomia ( 26853712) Diisocyanate-induced asthma ( 25918132) General risk tolerance (MTAG) ( 30643258) Hip circumference adjusted for BMI ( 28552196) Hippocampal volume ( 25625606) Idiopathic dilated cardiomyopathy ( 29495422) Intracranial aneurysm ( 29531279) Intraocular pressure ( 29617998 29785010 31959993 30054594) Knee osteoarthritis ( 18471798) Post bronchodilator FEV1/FVC ratio ( 26634245) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Blood protein levels ( 30072576)
Interacting Genes		9 interacting genes: CASK GAA INSC MARK2 PARD6B RBM5 RPS6KA1 YWHAE YWHAG	9 interacting genes: CPEB2 DYNC1LI2 EP300 HIVEP1 NCF1 NUMBL PARD3B SH3GLB2 STAT2
Entrez ID		117583	2548
HPRD ID		09795	06006
Ensembl ID		ENSG00000116117	ENSG00000171298
Uniprot IDs		Q8TEW8	P10253
PDB IDs			5KZW 5KZX 5NN3 5NN4 5NN5 5NN6 5NN8
Enriched GO Terms of Interacting Partners?
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