LY96 and SMARCB1

Number of citations of the paper that reports this interaction (PubMedID 27229929)
3

Data Source:
BioGRID (two hybrid)

		LY96	SMARCB1
Description		lymphocyte antigen 96	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Endosome Membrane Intrinsic Component Of Plasma Membrane Lipopolysaccharide Receptor Complex	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm Nucleolus SWI/SNF Complex Protein-containing Complex Brahma Complex Intracellular Membrane-bounded Organelle NpBAF Complex NBAF Complex
	Molecular Function	Lipopolysaccharide Binding Lipopolysaccharide Receptor Activity Protein Binding Coreceptor Activity Toll-like Receptor 4 Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase I CORE Element Sequence-specific DNA Binding P53 Binding DNA Binding Transcription Coactivator Activity Protein Binding Tat Protein Binding Nucleosomal DNA Binding
	Biological Process	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Cellular Defense Response Cell Surface Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Response To Lipopolysaccharide Detection Of Lipopolysaccharide Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Innate Immune Response Necroptotic Process Cellular Response To Lipopolysaccharide Apoptotic Signaling Pathway	RNA Polymerase I Preinitiation Complex Assembly DNA Repair Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cell Cycle Nervous System Development DNA Integration Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate ATP-dependent Chromatin Remodeling Positive Regulation By Host Of Viral Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K9 Dimethylation Negative Regulation Of Histone H3-K9 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Glucose Mediated Signaling Pathway Positive Regulation Of Histone H3-K9 Acetylation Regulation Of Histone H4-K16 Acetylation
Pathways		ER-Phagosome pathway Caspase activation via Death Receptors in the presence of ligand Toll Like Receptor 4 (TLR4) Cascade MyD88:MAL(TIRAP) cascade initiated on plasma membrane MyD88-independent TLR4 cascade TRIF-mediated programmed cell death MyD88 deficiency (TLR2/4) IRAK4 deficiency (TLR2/4) Regulation of TLR by endogenous ligand Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon IKK complex recruitment mediated by RIP1 TRAF6-mediated induction of TAK1 complex within TLR4 complex IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs		Morphine Methadone 3-Hydroxy-Myristic Acid Lauric Acid Myristic acid
Diseases
GWAS		Blood protein levels ( 29875488) Carotid plaque burden (smoking interaction) ( 24954085) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Postoperative atrial fibrillation in coronary artery bypass grafting surgery ( 26385043)	Fractional shortening ( 29403010) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) N-glycan levels ( 31163085)
Interacting Genes		7 interacting genes: CALM1 CDKN2C ELOC MLH1 SMARCB1 TLR2 TLR4	98 interacting genes: ABI2 AKT1 APP ARL11 ATP5F1A BCL2L11 BHLHE40 BLZF1 CALR CAMK2D CCDC120 CCDC33 CD69 CDC23 CDX2 CEBPB CHFR CXCL11 CYB5D2 DNAJA3 DPH6 FAM9B FUS GADD45G GATA1 GFAP GOLGA2 HNRNPM HOMEZ HOOK2 HSFY1 IHO1 IKZF3 KCTD9 KLC3 KLF1 KMT2B KMT2C KPNA6 KRT15 KRT19 KRT6A KRT6B KRT6C LDOC1 LENG8 LNX2 LY96 LZTS2 MAP1LC3B MAP3K20 MAPK8IP2 MBIP MCPH1 MECP2 MIF4GD MXI1 MYC NCK2 NONO NR0B2 NR3C1 OSGIN1 OTX2 PDPK1 PPP1CC PPP1R15A PRMT5 RAN RB1 RELB RINT1 RPN1 RPS6KA5 RXRA SAXO1 SIN3B SMARCA4 SRC TACC2 TAF1D TASOR2 TEKT5 TFIP11 TLE5 TNFAIP1 TNRC6A TP53 TRIM14 TRIM27 TSC22D4 UBQLN4 VIM XPO1 YEATS4 ZC3H11A ZDHHC17 ZNF398
Entrez ID		23643	6598
HPRD ID		05579	03364
Ensembl ID		ENSG00000154589	ENSG00000099956
Uniprot IDs		Q9Y6Y9	G5E975 Q12824 Q9H836
PDB IDs		1T2Z 2E56 2E59 2Z65 3FXI 3ULA 4G8A	5AJ1 5GJK 5L7A 5L7B 6AX5 6UCH
Enriched GO Terms of Interacting Partners?
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