LDOC1 and PRPF31

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		LDOC1	PRPF31
Description		LDOC1 regulator of NFKB signaling	pre-mRNA processing factor 31
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome MLL1 Complex Spliceosomal Tri-snRNP Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding U4 SnRNA Binding U4atac SnRNA Binding Ribonucleoprotein Complex Binding SnRNP Binding
	Biological Process	Maternal Placenta Development Negative Regulation Of Cell Proliferation Maternal Process Involved In Parturition Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Regulation Of Growth Hormone Activity	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome SnoRNA Localization Ribonucleoprotein Complex Localization
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS			Change in HbA1c levels in response to metformin treatment in type 2 diabetes ( 29650774)
Interacting Genes		68 interacting genes: AATF ABLIM1 AEBP2 AP1M1 ATF4 ATP6V1G1 BARD1 C1orf109 CCDC33 CCDC85B CEBPE CTNNBL1 DPF2 DPPA4 FAM107A FAM193B FAM50B FAM90A1 FOSL1 FXR2 GNL3L HAUS1 HDAC4 HGS IKZF3 IKZF5 INPP1 KRT15 KRT18 LATS1 LENG1 LNX1 MEAF6 MFAP1 MYC MZF1 NOD2 NRIP1 NXF1 PEG10 PLEKHF2 POLL PRPF31 PSMA1 PSMF1 RAB29 RNF6 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 TASOR2 TBC1D7 TLE5 TMSB4XP1 TNNT1 TTC23 UTP14A WT1 ZBTB16 ZBTB24 ZGPAT ZNF250 ZNF408 ZNF564 ZNF688 ZNF774	76 interacting genes: C1QTNF1 CALCOCO2 CBY2 CCDC136 CCDC33 CCDC57 CCNDBP1 CDCA7L CEP70 DVL2 EFEMP2 FANCA FANCC FASTK GOLGA2 HNRNPH2 HNRNPK JAKMIP2 KCTD6 KHDRBS2 KHDRBS3 KRT15 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 LDOC1 LURAP1 LZTS2 MDFI MEOX2 MID2 MIPOL1 MKRN3 MTUS2 NCAPH2 NDUFB9 NOTCH2NLA PAK5 PDE4DIP PHC2 PHF5A PNMA1 PNMA2 PPIH PRICKLE1 PRPF3 PSTPIP1 RACK1 RBM25 RBM4 RBMX RBMY1A1 RBMY1F RINT1 SIAH1 SNRNP200 SSX2IP STX11 TADA2A TFIP11 TLE5 TMCC2 TP53BP2 TRIM27 TRIM41 TSGA10 USP15 ZFP64 ZNF24 ZNF250 ZNF408 ZNF417 ZNF473 ZNF587
Entrez ID		23641	26121
HPRD ID		02322	05917
Ensembl ID		ENSG00000182195	ENSG00000105618
Uniprot IDs		O95751	Q8WWY3
PDB IDs			2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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