PATZ1 and MITF

Number of citations of the paper that reports this interaction (PubMedID 11751862)
8

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		PATZ1	MITF
Description		POZ/BTB and AT hook containing zinc finger 1	melanocyte inducing transcription factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Protein Dimerization Activity E-box Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Spermatogenesis Male Gonad Development T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Osteoclast Differentiation Melanocyte Differentiation Negative Regulation Of Cell Migration Regulation Of Cell Proliferation Camera-type Eye Development Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Cell Fate Commitment Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Bone Remodeling Protein-containing Complex Assembly Positive Regulation Of DNA-templated Transcription, Initiation Regulation Of RNA Biosynthetic Process
Pathways			SUMOylation of transcription factors
Drugs
Diseases			Ocular albinism; Ocular albinism, type I (OA1); Waardenburg syndrome, type II (WS2-OA) Waardenburg syndrome (WS) Malignant melanoma
GWAS		Height ( 31562340) Red cell distribution width ( 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Blond vs. brown/black hair color ( 30531825) Chronotype ( 30696823) Circulating fibroblast growth factor 23 levels ( 30217807) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Pulse pressure ( 27841878) QRS complex (12-leadsum) ( 27659466) Red blood cell count ( 27863252) Severe influenza A (H1N1) infection ( 26379185) Systolic blood pressure ( 27841878)
Interacting Genes		7 interacting genes: BACH1 BACH2 CLK1 MITF PRKAR1A RBPMS RNF4	29 interacting genes: APP CTNNB1 EBP EP300 FBXO7 FOS GSK3B HINT1 HK3 LEF1 MAPK1 MAPK14 MARK3 OTX2 PATZ1 PAX3 PAX6 PIAS1 PIAS2 PIAS3 PSMD14 RPS6KA1 SPI1 STUB1 SUMO1 TFE3 TFEB TFEC UBE2I
Entrez ID		23598	4286
HPRD ID		05522	01138
Ensembl ID		ENSG00000100105	ENSG00000187098
Uniprot IDs		A0A024R1F8 A0A024R1H7 A0A024R1M5 Q9HBE1	A0A087WXU1 B4DNC7 O75030 Q8WYR3
PDB IDs		2EPP 2EPQ 2EPR 2EPS 2YT9	4C7N
Enriched GO Terms of Interacting Partners?
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