TNPO3 and CHMP3

Number of citations of the paper that reports this interaction (PubMedID 16730941)
60

Data Source:
HPRD (two hybrid)

		TNPO3	CHMP3
Description		transportin 3	charged multivesicular body protein 3
Image
GO Annotations	Cellular Component	Nuclear Envelope Annulate Lamellae Cytoplasm Intracellular Membrane-bounded Organelle	ESCRT III Complex Cell Late Endosome Multivesicular Body Cytosol Plasma Membrane Cytoplasmic Vesicle Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Ran GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	Protein Binding Phosphatidylcholine Binding Ubiquitin-specific Protease Binding
	Biological Process	Protein Import Into Nucleus	Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Regulation Of Viral Process Protein Polymerization Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Negative Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion Regulation Of Early Endosome To Late Endosome Transport
Pathways			Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 24871463 26606652 23053960 26502338 18204098 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 21750679 31672989 30247649 29293537) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)	Glomerular filtration rate in chronic kidney disease ( 26420894)
Interacting Genes		4 interacting genes: CHMP3 SMURF2 SRSF1 TRA2B	13 interacting genes: APP CHMP2A CHMP2B CHMP4A CHMP4B FBXO7 IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2
Entrez ID		23534	51652
HPRD ID		18209	15650
Ensembl ID		ENSG00000064419	ENSG00000115561
Uniprot IDs		A0A024R794 B3KMX1 Q9Y5L0	Q9Y3E7
PDB IDs		4C0O 4C0P 4C0Q 4OL0 6GX9	2GD5 2XZE 3FRT 3FRV
Enriched GO Terms of Interacting Partners?
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