CHMP3 and STAMBP

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (pull down, affinity chromatography technology, fluorescent resonance energy transfer)
HPRD (in vitro, in vivo, two hybrid)

		CHMP3	STAMBP
Description		charged multivesicular body protein 3	STAM binding protein
Image
GO Annotations	Cellular Component	ESCRT III Complex Cell Late Endosome Multivesicular Body Cytosol Plasma Membrane Cytoplasmic Vesicle Late Endosome Membrane Extracellular Exosome	Nucleus Nucleoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidylcholine Binding Ubiquitin-specific Protease Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Protein Domain Specific Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity
	Biological Process	Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Regulation Of Viral Process Protein Polymerization Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Negative Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion Regulation Of Early Endosome To Late Endosome Transport	Mitotic Cytokinesis JAK-STAT Cascade Positive Regulation Of Cell Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Ras Protein Signal Transduction Protein K63-linked Deubiquitination
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III	Metalloprotease DUBs
Drugs
Diseases
GWAS		Glomerular filtration rate in chronic kidney disease ( 26420894)	Anti-saccade response ( 29064472) Blood metabolite levels ( 26401656) Serum metabolite levels ( 23093944)
Interacting Genes		13 interacting genes: APP CHMP2A CHMP2B CHMP4A CHMP4B FBXO7 IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2	43 interacting genes: ALAS1 AMN BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 NLRP7 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28
Entrez ID		51652	10617
HPRD ID		15650	05877
Ensembl ID		ENSG00000115561	ENSG00000124356
Uniprot IDs		Q9Y3E7	A0A140VK54 O95630
PDB IDs		2GD5 2XZE 3FRT 3FRV	2XZE 3RZU 3RZV 5IXF
Enriched GO Terms of Interacting Partners?
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