POFUT1 and ERGIC3

		POFUT1	ERGIC3
Description		protein O-fucosyltransferase 1	ERGIC and golgi 3
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane	Endoplasmic Reticulum Membrane COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Fucosyltransferase Activity Peptide-O-fucosyltransferase Activity
	Biological Process	Angiogenesis Somitogenesis Fucose Metabolic Process Regulation Of Transcription, DNA-templated Protein O-linked Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Fucosylation	ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER
Pathways		Pre-NOTCH Processing in the Endoplasmic Reticulum
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)	Cholesterol, total ( 24097068 25961943 20686565) Height ( 28552196) Hip circumference adjusted for BMI ( 28552196) Schizophrenia ( 28991256) Total cholesterol levels ( 28334899 30275531) Triglycerides ( 25961943) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		13 interacting genes: AKT2 DEFB115 DEFB116 DLL1 DUSP15 ERGIC3 ID1 JAG1 NAP1L2 NOTCH1 PTPRA USH2A ZIC3	3 interacting genes: ERGIC1 POFUT1 UBE2D3
Entrez ID		23509	51614
HPRD ID		06319	15306
Ensembl ID		ENSG00000101346	ENSG00000125991
Uniprot IDs		Q9H488	A2TJK5 Q9Y282
PDB IDs		5UX6 5UXH
Enriched GO Terms of Interacting Partners?
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