ISCU and AGTRAP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ISCU	AGTRAP
Description		iron-sulfur cluster assembly enzyme	angiotensin II receptor associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Iron Ion Binding Protein Binding Ferrous Iron Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding Molecular Adaptor Activity	Angiotensin Type II Receptor Activity Protein Binding
	Biological Process	Cellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly Small Molecule Metabolic Process Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Aconitate Hydratase Activity Negative Regulation Of Ferrous Iron Import Across Plasma Membrane	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways			Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Intraocular pressure ( 29617998)	Systolic blood pressure ( 19430483)
Interacting Genes		13 interacting genes: AGTRAP BANP CCDC172 FAM9B GOLGA2 HPRT1 HSCB IKZF1 KRT40 LNX1 MID2 NECAB2 NUP62	79 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 ARHGAP1 BPIFA2 CAPNS1 CD160 CIAO2A COQ8A CPLX1 CRCT1 DDA1 DDX55 DGCR6 DIABLO ECPAS FAM114A1 FAM160A2 FARS2 FASTKD3 FATE1 FGA GABARAPL2 GAD1 GAD2 GDNF GTF3C1 H4C7 HARS2 HMGB1 HSCB HSPA4 ISCU LMNA LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH MYG1 NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PIMREG PITPNC1 PNPO PTPN9 RACK1 RMDN2 S100B SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TMEM14B TPD52L3 TUBA1B TXN2 UBE2I ZFYVE21 ZNF391
Entrez ID		23479	57085
HPRD ID		14828	16379
Ensembl ID		ENSG00000136003	ENSG00000177674
Uniprot IDs		A0A024RBI3 B1P7G3 B3KQ30 B4DNC9 Q9H1K1	Q6RW13
PDB IDs		5KZ5 5WKP 5WLW 6NZU 6UXE
Enriched GO Terms of Interacting Partners?
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