AGTRAP and GABARAPL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AGTRAP	GABARAPL2
Description		angiotensin II receptor associated protein	GABA type A receptor associated protein like 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Autophagosome Membrane Intracellular Cytoplasm Autophagosome Golgi Apparatus Cytosol Cytoplasmic Vesicle
	Molecular Function	Angiotensin Type II Receptor Activity Protein Binding	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding
	Biological Process	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways		Signaling by BRAF and RAF fusions	Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS		Systolic blood pressure ( 19430483)	Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)
Interacting Genes		79 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 ARHGAP1 BPIFA2 CAPNS1 CD160 CIAO2A COQ8A CPLX1 CRCT1 DDA1 DDX55 DGCR6 DIABLO ECPAS FAM114A1 FAM160A2 FARS2 FASTKD3 FATE1 FGA GABARAPL2 GAD1 GAD2 GDNF GTF3C1 H4C7 HARS2 HMGB1 HSCB HSPA4 ISCU LMNA LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH MYG1 NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PIMREG PITPNC1 PNPO PTPN9 RACK1 RMDN2 S100B SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TMEM14B TPD52L3 TUBA1B TXN2 UBE2I ZFYVE21 ZNF391	66 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CLN8 CUL3 EGFR FUNDC1 GIMAP6 GOSR1 GPR37 KASH5 KBTBD6 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NSF OPTN OSBPL7 PRKAR2A PTPRA RAP1A RAP2A RB1CC1 RCN2 RPS2 SGTA SIK2 SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP1 TP53INP2 TRIM21 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ
Entrez ID		57085	11345
HPRD ID		16379	16246
Ensembl ID		ENSG00000177674	ENSG00000034713
Uniprot IDs		Q6RW13	P60520
PDB IDs			4CO7
Enriched GO Terms of Interacting Partners?
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