RHOBTB2 and RHOBTB3

Number of citations of the paper that reports this interaction (PubMedID 18835386)
30

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		RHOBTB2	RHOBTB3
Description		Rho related BTB domain containing 2	Rho related BTB domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Trans-Golgi Network Membrane Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding	GTPase Activity Protein Binding ATP Binding GTP Binding ATPase Activity Rab GTPase Binding Protein Kinase Binding
	Biological Process	Cytokinesis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Motor Neuron Axon Guidance Regulation Of Cell Shape Male Gonad Development Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Retrograde Transport, Endosome To Golgi Engulfment Of Apoptotic Cell
Pathways		Rho GTPase cycle	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Height ( 28552196) Plasma trimethylamine N-oxide levels ( 28439531) Renal cell carcinoma ( 28598434) Survival in breast cancer (estrogen-receptor positive) ( 29423119)
Interacting Genes		12 interacting genes: BAG4 CHEK2 CUL5 ERBB2 FGFR2 HSP90AA1 HSP90AB1 PALB2 PPM1D PTPN1 RHOBTB3 STK11	10 interacting genes: BHLHE40 CCNE1 CUL3 HGS RAB9A RBPMS RBX1 RHOBTB2 UBXN11 VHL
Entrez ID		23221	22836
HPRD ID		06300	09557
Ensembl ID		ENSG00000008853	ENSG00000164292
Uniprot IDs		Q9BYZ6	O94955
PDB IDs
Enriched GO Terms of Interacting Partners?
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