TBC1D1 and GABARAPL1

Number of citations of the paper that reports this interaction (PubMedID 22354992)
74

Data Source:
BioGRID (pull down)

		TBC1D1	GABARAPL1
Description		TBC1 domain family member 1	GABA type A receptor associated protein like 1
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GO Annotations	Cellular Component	Nucleus Cytosol	Autophagosome Membrane Intracellular Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding	Protein Binding Microtubule Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Intracellular Protein Transport Regulation Of Protein Localization Membrane Organization Activation Of GTPase Activity Regulation Of Cilium Assembly	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Macroautophagy Autophagosome Maturation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane	Macroautophagy
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals ( 22959728) Crohn's disease ( 23850713 23266558) Diastolic blood pressure ( 27841878 27618452) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Neutrophil percentage of white cells ( 27863252) Periodontal microbiota ( 22699663) Pulse pressure ( 27841878) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301) Systolic blood pressure ( 27841878 27618452) Verbal declarative memory ( 25648963) Weight ( 28552196)
Interacting Genes		5 interacting genes: GABARAPL1 HSPB1 MAP1LC3A SMAD2 YWHAG	47 interacting genes: AHNAK2 AMBRA1 ANK2 ATG13 ATG4A ATG4D CALCOCO2 CUL3 DVL2 FUNDC1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAPK15 MEFV NEDD4 OPRK1 OPTN RABGAP1 RABGAP1L RB1CC1 RETREG3 SCYL3 SNCA SQSTM1 SRPK1 SRPK2 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TRIM21 ULK1 VDR WDFY3
Entrez ID		23216	23710
HPRD ID		18161	07601
Ensembl ID		ENSG00000065882	ENSG00000139112
Uniprot IDs		B9A6J6 Q6PJJ8 Q86TI0 Q8NC59	A0A024RAP5 Q9H0R8
PDB IDs		3QYE	2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL
Enriched GO Terms of Interacting Partners?
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