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JMJD6 and SLFN12
Number of citations of the paper that reports this interaction (PubMedID
23455924
)
38
Data Source:
BioGRID
(two hybrid)
JMJD6
SLFN12
Description
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
schlafen family member 12
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Ribonucleoprotein Complex
Molecular Function
Transcription Coactivator Activity
RNA Binding
Single-stranded RNA Binding
Iron Ion Binding
Protein Binding
Demethylase Activity
Histone Demethylase Activity
Histone Demethylase Activity (H3-R2 Specific)
Histone Demethylase Activity (H4-R3 Specific)
Oxidative RNA Demethylase Activity
Signaling Receptor Activity
Identical Protein Binding
Peptidyl-lysine 5-dioxygenase Activity
P-TEFb Complex Binding
Biological Process
Kidney Development
Sprouting Angiogenesis
MRNA Processing
Protein Demethylation
Cell Surface Receptor Signaling Pathway
Heart Development
RNA Splicing
Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine
Lung Development
T Cell Differentiation In Thymus
Oxidative RNA Demethylation
Macrophage Activation
Recognition Of Apoptotic Cell
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of MRNA Splicing, Via Spliceosome
Erythrocyte Development
Protein Homooligomerization
Retina Development In Camera-type Eye
Histone H3-R2 Demethylation
Histone H4-R3 Demethylation
Pathways
HDMs demethylate histones
Drugs
Diseases
GWAS
Retinal arteriolar caliber (
23776548
)
Interacting Genes
27 interacting genes:
AEBP2
ANKEF1
BAG5
C17orf97
CCNL1
CENPL
DIP2A
FGD5
FRMD6
GNA14
H2BC11
H3C1
H4C1
HMGXB4
LARP7
NAA50
NFIX
NHP2
PRPF38A
PSMC1
RSPO2
SLFN12
SLU7
STAC3
TAF1A
U2AF1
ZNF451
2 interacting genes:
JMJD6
SUV39H1
Entrez ID
23210
55106
HPRD ID
05371
08543
Ensembl ID
ENSG00000070495
ENSG00000172123
Uniprot IDs
Q6NYC1
Q8IYM2
PDB IDs
3K2O
3LD8
3LDB
6BNH
6GDY
6MEV
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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