JMJD6 and DIP2A

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		JMJD6	DIP2A
Description		jumonji domain containing 6, arginine demethylase and lysine hydroxylase	disco interacting protein 2 homolog A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Ribonucleoprotein Complex	Nucleus Cell Surface
	Molecular Function	Transcription Coactivator Activity RNA Binding Single-stranded RNA Binding Iron Ion Binding Protein Binding Demethylase Activity Histone Demethylase Activity Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Oxidative RNA Demethylase Activity Signaling Receptor Activity Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity P-TEFb Complex Binding	Catalytic Activity Protein Binding
	Biological Process	Kidney Development Sprouting Angiogenesis MRNA Processing Protein Demethylation Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Oxidative RNA Demethylation Macrophage Activation Recognition Of Apoptotic Cell Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Protein Homooligomerization Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation	Multicellular Organism Development Negative Regulation Of Gene Expression Regulation Of Apoptotic Process
Pathways		HDMs demethylate histones
Drugs
Diseases
GWAS		Retinal arteriolar caliber ( 23776548)	Anti-saccade response ( 29064472) Lymphocyte counts ( 27863252) Pulse pressure ( 30224653)
Interacting Genes		27 interacting genes: AEBP2 ANKEF1 BAG5 C17orf97 CCNL1 CENPL DIP2A FGD5 FRMD6 GNA14 H2BC11 H3C1 H4C1 HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZNF451	18 interacting genes: ADAMTSL4 CCDC33 CEP44 DAB2 DLX2 FAM214B GPATCH2L JMJD6 MBIP PSME3 PTPN3 SORBS3 STAC3 TLE5 TMCC2 TRIM39 TRIP13 ZBTB43
Entrez ID		23210	23181
HPRD ID		05371	07611
Ensembl ID		ENSG00000070495	ENSG00000160305
Uniprot IDs		Q6NYC1	Q14689 Q96NX2
PDB IDs		3K2O 3LD8 3LDB 6BNH 6GDY 6MEV
Enriched GO Terms of Interacting Partners?
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