PMPCA and AVEN

		PMPCA	AVEN
Description		peptidase, mitochondrial processing subunit alpha	apoptosis and caspase activation inhibitor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Processing Peptidase Complex	Cytosol Endomembrane System Membrane
	Molecular Function	Endopeptidase Activity Metalloendopeptidase Activity Metal Ion Binding	Protein Binding
	Biological Process	Proteolysis Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport	Apoptotic Process Negative Regulation Of Apoptotic Process
Pathways		Mitochondrial protein import Processing of SMDT1	Formation of apoptosome Regulation of the apoptosome activity
Drugs
Diseases
GWAS		Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)
Interacting Genes		13 interacting genes: ASS1 AVEN BMPR2 KIF2C NDOR1 NPSR1 NSMF OLFM1 PCDHB4 PMPCB SCUBE1 SKIV2L UBAC1	4 interacting genes: APAF1 BCL2L1 PMPCA SMURF1
Entrez ID		23203	57099
HPRD ID		07500	05588
Ensembl ID		ENSG00000165688	ENSG00000169857
Uniprot IDs		Q10713	Q9NQS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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