MESD and SNX5

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		MESD	SNX5
Description		mesoderm development LRP chaperone	sorting nexin 5
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Plasma Membrane	Ruffle Phagocytic Cup Endosome Cytosol Brush Border Cytoplasmic Vesicle Membrane Retromer Complex Retromer, Tubulation Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Extrinsic Component Of Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Macropinocytic Cup Tubular Endosome
	Molecular Function	Molecular_function Identical Protein Binding Low-density Lipoprotein Particle Receptor Binding	Protein Binding Phosphatidylinositol-5-phosphate Binding D1 Dopamine Receptor Binding Dynactin Binding Phosphatidylinositol Binding Cadherin Binding Protein Heterodimerization Activity Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Intracellular Protein Transport Pinocytosis Epidermal Growth Factor Catabolic Process Regulation Of Macroautophagy Positive Regulation Of Renal Sodium Excretion Retrograde Transport, Endosome To Golgi Negative Regulation Of Blood Pressure Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Insulin Receptor Signaling Pathway
Pathways			Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS			Cholesterol, total ( 25961943) LDL cholesterol ( 24097068 25961943) LDL cholesterol levels ( 28334899 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		10 interacting genes: APP ATP6V1E1 BRD4 KPNB1 LRP5 MTNR1A PSMA5 RFC3 SNX5 SNX7	15 interacting genes: APPBP2 AQP2 CDC37 CLTC CLTCL1 DNAJB11 FANCA HGS HMOX2 ITSN1 MESD MIB1 PFDN1 PRKRA SNX2
Entrez ID		23184	27131
HPRD ID		12129	10439
Ensembl ID		ENSG00000117899	ENSG00000089006
Uniprot IDs		Q14696	Q6P5V6 Q9Y5X3
PDB IDs			1SYS 5TGH 5TGI 5TGJ 5WY2 6N5X 6N5Y 6N5Z
Enriched GO Terms of Interacting Partners?
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