CIC and PYCR2

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

		CIC	PYCR2
Description		capicua transcriptional repressor	pyrroline-5-carboxylate reductase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Matrix
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding	Pyrroline-5-carboxylate Reductase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development	Proline Biosynthetic Process Cellular Amino Acid Biosynthetic Process Cellular Response To Oxidative Stress Oxidation-reduction Process L-proline Biosynthetic Process
Pathways			Glutamate and glutamine metabolism
Drugs			NADH L-Proline
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077)
Interacting Genes		14 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GTPBP3 NFYC PICK1 PLD3 PLK1 PYCR2 SEC62 SETD2 TRIM22 ZNRD1	3 interacting genes: APP CIC SKIL
Entrez ID		23152	29920
HPRD ID		10831	17939
Ensembl ID		ENSG00000079432	ENSG00000143811
Uniprot IDs		A0A0A0MQR4 Q96RK0	A0A087WTV6 A0A0S2Z5U6 Q96C36
PDB IDs		2M41 4J2J 4J2L 6JRP
Enriched GO Terms of Interacting Partners?
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