CIC and PLD3

		CIC	PLD3
Description		capicua transcriptional repressor	phospholipase D family member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Protein-containing Complex Intracellular Membrane-bounded Organelle	Golgi Membrane Lysosomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Endosome Membrane Late Endosome Membrane Lysosomal Lumen Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding	Phospholipase D Activity Protein Binding Single-stranded DNA 5'-3' Exodeoxyribonuclease Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated Lung Alveolus Development	Immune System Process DNA Metabolic Process Inflammatory Response Myotube Differentiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways			Synthesis of PG Role of phospholipids in phagocytosis
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077)	Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)
Interacting Genes		14 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GTPBP3 NFYC PICK1 PLD3 PLK1 PYCR2 SEC62 SETD2 TRIM22 ZNRD1	11 interacting genes: ANXA7 ATG16L1 BCL2L1 CIC HGS NFKB1 SOX4 SPP1 STK11 TK1 VRK2
Entrez ID		23152	23646
HPRD ID		10831	07148
Ensembl ID		ENSG00000079432	ENSG00000105223
Uniprot IDs		A0A0A0MQR4 Q96RK0	A0A024R0Q4 Q8IV08
PDB IDs		2M41 4J2J 4J2L 6JRP
Enriched GO Terms of Interacting Partners?
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