FLI1 and SOX30

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FLI1	SOX30
Description		Fli-1 proto-oncogene, ETS transcription factor	SRY-box transcription factor 30
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Nuclear Body	Nuclear Chromatin Nucleus Cytoplasm Chromocenter
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Beta-catenin Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Hemostasis Blood Circulation Animal Organ Morphogenesis Cell Differentiation Megakaryocyte Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Spermatid Development Negative Regulation Of Wnt Signaling Pathway Response To Corticosteroid Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Transcriptional regulation of granulopoiesis
Drugs
Diseases		Ewing's sarcoma
GWAS		Albumin-globulin ratio ( 29403010) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Corneal astigmatism ( 30306274) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Heel bone mineral density ( 30598549) Height ( 20881960 31562340) Left ventricular obstructive tract defect (inherited effect) ( 28468790) Myopia (pathological) ( 23049088) Non-albumin protein levels ( 29403010) Platelet count ( 27863252) Plateletcrit ( 27863252) Rheumatoid arthritis ( 22446963) Rheumatoid arthritis (ACPA-positive) ( 24532676) Systemic lupus erythematosus ( 27399966 26502338) Vitiligo ( 27723757)	Glycated hemoglobin levels ( 28898252) Triglyceride levels ( 31647587)
Interacting Genes		18 interacting genes: BRCA1 CTBP2 ELK1 ERG ETV6 EWSR1 GATA1 KLF1 PIAS1 PIAS2 PRKCD SIAH1 SMAD3 SMAD9 SOX30 SRF TDP2 UBE2I	18 interacting genes: AHCYL1 AURKA BAMBI BRCA1 CFAP206 CUL5 DCAF4 DDX56 FBXO38 FLI1 GNAI3 GP2 KIFC3 MRPS5 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		2313	11063
HPRD ID		01901	09461
Ensembl ID		ENSG00000151702	ENSG00000039600
Uniprot IDs		A0A024R3K4 A0A024R3M5 A0A024R3N6 Q01543	B4DXW7 O94993
PDB IDs		1FLI 1X66 2YTU 5E8G 5E8I 5JVT
Enriched GO Terms of Interacting Partners?
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