CDK19 and SRSF7

Number of citations of the paper that reports this interaction (PubMedID 12501247)
40

Data Source:
BioGRID (enzymatic study)
HPRD (in vivo)

		CDK19	SRSF7
Description		cyclin dependent kinase 19	serine and arginine rich splicing factor 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Mediator Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Extracellular Exosome
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity	RNA Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding
	Biological Process	Protein Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of Inflammatory Response Regulation Of Cell Cycle Cellular Response To Lipopolysaccharide	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Zinc levels ( 26025379)
Interacting Genes		8 interacting genes: BCL6 EIF3F PRMT5 SMARCA4 SRSF7 SUZ12 USP54 WDR77	14 interacting genes: CCNL2 CDK19 CDK6 CLK1 CPSF6 DUSP11 FBXO7 NEDD4 NXF1 PCBP2 SDCBP SREK1 SRPK1 SRPK2
Entrez ID		23097	6432
HPRD ID		07627	08991
Ensembl ID		ENSG00000155111	ENSG00000115875
Uniprot IDs		B4DUB1 I6W807 Q9BWU1	Q16629
PDB IDs			2HVZ
Enriched GO Terms of Interacting Partners?
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