PPRC1 and NRF1

Number of citations of the paper that reports this interaction (PubMedID 11340167)
108

Data Source:
HPRD (in vitro, in vivo)

		PPRC1	NRF1
Description		PPARG related coactivator 1	nuclear respiratory factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Transcription Coregulator Activity RNA Binding Transcription Factor Binding Nuclear Receptor Transcription Coactivator Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity
	Biological Process	Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity	Generation Of Precursor Metabolites And Energy Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Transcriptional activation of mitochondrial biogenesis	PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 27863252) Metabolite levels ( 23823483)	Bipolar disorder ( 31043756) Obesity-related traits ( 23251661) Platelet count ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Response to antidepressants and depression ( 27622933)
Interacting Genes		2 interacting genes: MCPH1 NRF1	13 interacting genes: CSNK2A1 DYNLL1 FHL2 LHX4 MAFF PARP1 PLXDC1 POGZ PPARGC1A PPRC1 SIAH2 SP4 TRAF2
Entrez ID		23082	4899
HPRD ID		15173	02930
Ensembl ID		ENSG00000148840	ENSG00000106459
Uniprot IDs		E7EVG6 Q5VV67	A0A024R770 A0A024R774 Q16656
PDB IDs
Enriched GO Terms of Interacting Partners?
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