PDZRN3 and EFNB2

Number of citations of the paper that reports this interaction (PubMedID 15458844)
67

Data Source:
HPRD (two hybrid)

		PDZRN3	EFNB2
Description		PDZ domain containing ring finger 3	ephrin B2
Image
GO Annotations	Cellular Component	Cytoplasm Cell Junction Neuromuscular Junction	Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Focal Adhesion Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ubiquitin Protein Ligase Activity	Virus Receptor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	Neuromuscular Junction Development Protein Ubiquitination	Lymph Vessel Development Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Proliferation Anatomical Structure Morphogenesis Animal Organ Morphogenesis Negative Regulation Of Keratinocyte Proliferation Negative Regulation Of Neuron Projection Development T Cell Costimulation Adherens Junction Organization Viral Entry Into Host Cell Ephrin Receptor Signaling Pathway Blood Vessel Morphogenesis Venous Blood Vessel Morphogenesis Regulation Of Chemotaxis Nephric Duct Morphogenesis Presynapse Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Positive Regulation Of Neuron Death Positive Regulation Of Aorta Morphogenesis Positive Regulation Of Cardiac Muscle Cell Differentiation
Pathways			EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767) Mercury levels ( 26025379) Mitochondrial DNA copy number (white blood cells) ( 30704525) PR interval ( 30679814 30046033)	Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Subcutaneous adipose tissue ( 26480920)
Interacting Genes		6 interacting genes: BMPR2 EFNB2 LNX1 LNX2 RPS6KA1 UBE2D2	21 interacting genes: DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RGS3 RHBDL2 SDCBP SRC
Entrez ID		23024	1948
HPRD ID		15115	02754
Ensembl ID		ENSG00000121440	ENSG00000125266
Uniprot IDs		B7Z2I8 B7Z5Q3 B7Z5X9 B7ZAG0 E7ENB6 Q9UPQ7	P52799
PDB IDs		1UHP 1WH1	2HLE 2I85 2VSK 2VSM 2WO2 3GXU 4UF7 6P7Y 6PDL
Enriched GO Terms of Interacting Partners?
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