EFNB2 and RGS3

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		EFNB2	RGS3
Description		ephrin B2	regulator of G protein signaling 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Focal Adhesion Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Presynaptic Membrane Integral Component Of Postsynaptic Density Membrane	Nucleus Cytosol Plasma Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Ephrin Receptor Binding	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Lymph Vessel Development Cell Migration Involved In Sprouting Angiogenesis Cell Adhesion Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Proliferation Anatomical Structure Morphogenesis Animal Organ Morphogenesis Negative Regulation Of Keratinocyte Proliferation Negative Regulation Of Neuron Projection Development T Cell Costimulation Adherens Junction Organization Viral Entry Into Host Cell Ephrin Receptor Signaling Pathway Blood Vessel Morphogenesis Venous Blood Vessel Morphogenesis Regulation Of Chemotaxis Nephric Duct Morphogenesis Presynapse Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Positive Regulation Of Neuron Death Positive Regulation Of Aorta Morphogenesis Positive Regulation Of Cardiac Muscle Cell Differentiation	Inactivation Of MAPK Activity G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways		EPH-Ephrin signaling EPH-Ephrin signaling EPHB-mediated forward signaling EPHB-mediated forward signaling Ephrin signaling Ephrin signaling EPH-ephrin mediated repulsion of cells	G alpha (q) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Subcutaneous adipose tissue ( 26480920)	Height ( 28552196)
Interacting Genes		21 interacting genes: DLG4 EPHA3 EPHA4 EPHB1 EPHB2 EPHB4 EPHB6 GRIP1 GRM1 GRM5 HOMER1 NCK2 PDZRN3 PECAM1 PICK1 PSEN1 PTPN13 RGS3 RHBDL2 SDCBP SRC	23 interacting genes: ACD APP CNKSR2 DEPDC1B EFNB1 EFNB2 ESR1 GLS2 GNA11 GNAI3 GORASP2 GRIN2A HES4 HIPK3 MAPK12 PAX6 PLSCR1 PRKN SCN5A YWHAB YWHAE YWHAQ YWHAZ
Entrez ID		1948	5998
HPRD ID		02754	03720
Ensembl ID		ENSG00000125266	ENSG00000138835
Uniprot IDs		P52799	A0A024R831 A0A024R833 A0A024R841 B3KVT7 B3KWG8 H7BXY1 P49796 Q53GP3
PDB IDs		2HLE 2I85 2VSK 2VSM 2WO2 3GXU 4UF7 6P7Y 6PDL	2F5Y 2OJ4 3FBK
Enriched GO Terms of Interacting Partners?
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