ACIN1 and PAFAH1B2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACIN1	PAFAH1B2
Description		apoptotic chromatin condensation inducer 1	platelet activating factor acetylhydrolase 1b catalytic subunit 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane Nuclear Speck ASAP Complex	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding ATPase Activity Enzyme Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Platelet-activating Factor Acetyltransferase Activity
	Biological Process	MRNA Processing RNA Splicing Erythrocyte Differentiation Apoptotic Chromosome Condensation Positive Regulation Of Monocyte Differentiation	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy Neutrophil Degranulation
Pathways		Apoptotic cleavage of cellular proteins	Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Protein quantitative trait loci ( 18464913) Systolic blood pressure ( 30578418)
Interacting Genes		10 interacting genes: ABCF3 AKR1C3 BTBD10 CASP3 CSNK2A1 KLHL26 PAFAH1B2 PCBD1 SRPK2 YWHAG	16 interacting genes: ACIN1 ASF1A CCT3 CRK PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 ZFP36L1
Entrez ID		22985	5049
HPRD ID		05191	03940
Ensembl ID		ENSG00000100813	ENSG00000168092
Uniprot IDs		B4DQZ7 Q9UKV3	P68402 V9HW44
PDB IDs		6G6S	1VYH
Enriched GO Terms of Interacting Partners?
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