TCF25 and RPS10

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		TCF25	RPS10
Description		transcription factor 25	ribosomal protein S10
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Nucleolus Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Heart Development	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases			Diamond-Blackfan anemia (DBA)
GWAS		Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Monobrow ( 27182965) Red vs. brown/black hair color ( 30531825) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Rosacea symptom severity ( 29771307)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Estimated glomerular filtration rate ( 31015462 30604766)
Interacting Genes		9 interacting genes: APPBP2 DERL1 GPRASP2 KASH5 LRRK1 MAGEA11 NEK2 RPS10 SAT1	15 interacting genes: APP DMPK DNMT3B DVL3 EED FBXO25 HAP1 HIP1 KAT7 PFN2 PTTG1 SYK TCF25 WIZ XRCC6
Entrez ID		22980	6204
HPRD ID		13830	04697
Ensembl ID		ENSG00000141002	ENSG00000124614
Uniprot IDs		Q9BQ70	P46783
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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