RPS10 and PTTG1

Number of citations of the paper that reports this interaction (PubMedID 9915854)
4

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		RPS10	PTTG1
Description		ribosomal protein S10	PTTG1 regulator of sister chromatid separation, securin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding SH3 Domain Binding
	Biological Process	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	DNA Repair Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Spermatogenesis Negative Regulation Of Endopeptidase Activity Anaphase-promoting Complex-dependent Catabolic Process Homologous Chromosome Segregation Chromosome Organization Cell Division Negative Regulation Of Mitotic Sister Chromatid Separation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	APC/C:Cdc20 mediated degradation of Securin APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Separation of Sister Chromatids
Drugs
Diseases		Diamond-Blackfan anemia (DBA)
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Estimated glomerular filtration rate ( 31015462 30604766)	Dermatomyositis or juvenile dermatomyositis ( 26362759) Insulin-related traits ( 22791750) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 21408207 28714469 19838195) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)
Interacting Genes		15 interacting genes: APP DMPK DNMT3B DVL3 EED FBXO25 HAP1 HIP1 KAT7 PFN2 PTTG1 SYK TCF25 WIZ XRCC6	22 interacting genes: ANAPC11 ANAPC2 AURKA CAMK2A CDC20 CDC27 CDC34 CDK1 CRK CUL1 DNAJA1 FZR1 PLCG2 PPP2R2D PPP2R5A PRKN PTTG1IP RPS10 TP53 UBE2N UBE4A XRCC6
Entrez ID		6204	9232
HPRD ID		04697	04998
Ensembl ID		ENSG00000124614	ENSG00000164611
Uniprot IDs		P46783	O95997 Q6IAL9
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?