RAB18 and PRTFDC1

		RAB18	PRTFDC1
Description		RAB18, member RAS oncogene family	phosphoribosyl transferase domain containing 1
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GO Annotations	Cellular Component	Intracellular Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Endomembrane System Secretory Granule Membrane Synapse Endoplasmic Reticulum Tubular Network
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Eye Development Intracellular Protein Transport Small GTPase Mediated Signal Transduction Brain Development Rab Protein Signal Transduction Lipid Droplet Organization Neutrophil Degranulation Import Into Nucleus Endoplasmic Reticulum Tubular Network Organization	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process
Pathways		Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Warburg micro syndrome
GWAS		Childhood ear infection ( 27182965 28928442) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196)	Diisocyanate-induced asthma ( 25918132) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 27863252) Plateletcrit ( 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252)
Interacting Genes		13 interacting genes: APBB1IP CHM DVL3 ERRFI1 FAM107A PDE6D PPP2R1A PPP2R1B PRTFDC1 TAX1BP1 TOM1L1 TREH UCN	14 interacting genes: DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B MCMBP NIF3L1 RAB18 STAT5A TCL1A TMEM14B
Entrez ID		22931	56952
HPRD ID		03731	17917
Ensembl ID		ENSG00000099246	ENSG00000099256
Uniprot IDs		A0A087X163 B7Z4P9 B7Z5V3 Q9NP72	Q9NRG1
PDB IDs		1X3S	2JBH
Enriched GO Terms of Interacting Partners?
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