SEC31A and PEF1

Number of citations of the paper that reports this interaction (PubMedID 27716508)
29

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		SEC31A	PEF1
Description		SEC31 homolog A, COPII coat complex component	penta-EF-hand domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Vesicle Coat COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Golgi Membrane Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Calcium-dependent Protein Binding	RNA Binding Calcium Ion Binding Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Protein Binding, Bridging Involved In Substrate Recognition For Ubiquitination
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II IRE1-mediated Unfolded Protein Response COPII Vesicle Coating Response To Calcium Ion Cargo Loading Into COPII-coated Vesicle COPII-coated Vesicle Budding	ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination
Pathways		COPII-mediated vesicle transport MHC class II antigen presentation XBP1(S) activates chaperone genes Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs			Calcium Citrate Calcium Phosphate
Diseases
GWAS		Adult asthma ( 27611488) Neutrophil percentage of white cells ( 27863252)	Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)
Interacting Genes		12 interacting genes: APC ARIH1 KLHL12 PDCD6 PEF1 PFDN1 PRNP REL SEC13 TNNT1 TSC22D2 USP8	14 interacting genes: ALG2 CALCOCO2 CEP55 CUL3 DAZAP2 DMRTB1 EWSR1 FOXR2 HGS KLHL12 NR0B2 PDCD6 SEC31A TFG
Entrez ID		22872	553115
HPRD ID		15314	10143
Ensembl ID		ENSG00000138674	ENSG00000162517
Uniprot IDs		A0A024RDH6 A1LU61 O94979	A0A384MQX5 Q9UBV8
PDB IDs		3WXA
Enriched GO Terms of Interacting Partners?
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