EXOC4 and BIRC6

Number of citations of the paper that reports this interaction (PubMedID 18329369)
73

Data Source:
HPRD (in vivo)

		EXOC4	BIRC6
Description		exocyst complex component 4	baculoviral IAP repeat containing 6
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cell Cytoplasm Cytosol Plasma Membrane Microvillus Membrane Growth Cone Membrane Myelin Sheath Abaxonal Region Synapse Flemming Body	Spindle Pole Nucleus Endosome Trans-Golgi Network Microtubule Organizing Center Membrane Midbody Flemming Body
	Molecular Function	Protein Binding Ral GTPase Binding PDZ Domain Binding Protein N-terminus Binding	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Targeting To Membrane Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Chemical Synaptic Transmission Regulation Of Macroautophagy Paraxial Mesoderm Formation Vesicle Tethering Involved In Exocytosis	Protein Phosphorylation Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Cell Cycle Positive Regulation Of Cell Proliferation Negative Regulation Of Endopeptidase Activity Protein Ubiquitination Regulation Of Cytokinesis Regulation Of Cell Proliferation Negative Regulation Of Apoptotic Process Cell Division Labyrinthine Layer Development Spongiotrophoblast Layer Development Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Food allergy ( 29030101) General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Moderate to vigorous physical activity levels ( 29899525) Mood instability ( 31168069) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) QT interval ( 29213071) Response to selective serotonin reuptake inhibitors in depression ( 30034349) Tonometry ( 17903302) Vigorous physical activity ( 29899525)	Chronotype ( 30696823) Coffee consumption ( 31046077) General risk tolerance (MTAG) ( 30643258) Male-pattern baldness ( 28196072) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		9 interacting genes: BIRC6 CEP63 DISC1 DLG3 DLG4 DLGAP4 EXOC7 GRIN2B RALA	19 interacting genes: BIRC5 CASP3 CASP7 CASP8 CASP9 CDK1 CSNK2A1 DIABLO EXOC3 EXOC4 GABARAP HTRA2 MAP2K1 PLK1 RAB8A RNF41 UBE2D1 USP8 VAV2
Entrez ID		60412	57448
HPRD ID		12185	05731
Ensembl ID		ENSG00000131558	ENSG00000115760
Uniprot IDs		Q6NX51 Q96A65	Q9NR09
PDB IDs			3CEG
Enriched GO Terms of Interacting Partners?
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