FKBP1B and GMCL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FKBP1B	GMCL1
Description		FKBP prolyl isomerase 1B	germ cell-less 1, spermatogenesis associated
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Membrane Z Disc Sarcoplasmic Reticulum Membrane Calcium Channel Complex	Nucleus Nuclear Matrix
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Ryanodine-sensitive Calcium-release Channel Activity Protein Binding FK506 Binding Calcium Channel Inhibitor Activity Cyclic Nucleotide Binding Ion Channel Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization 'de Novo' Protein Folding Smooth Muscle Contraction Response To Glucose Negative Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Neuronal Action Potential Propagation Protein Maturation By Protein Folding Insulin Secretion Negative Regulation Of Phosphoprotein Phosphatase Activity Response To Vitamin E Ion Transmembrane Transport Calcium-mediated Signaling Using Intracellular Calcium Source Protein Refolding T Cell Proliferation Response To Hydrogen Peroxide Positive Regulation Of Axon Regeneration Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Cytosolic Calcium Ion Concentration Response To Redox State Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Chaperone-mediated Protein Folding Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cardiac Conduction	Multicellular Organism Development Spermatogenesis Cell Differentiation
Pathways		Stimuli-sensing channels Ion homeostasis
Drugs
Diseases
GWAS		Chronotype ( 27494321) Quantitative traits ( 19197348)	Atrial fibrillation ( 28416818 30061737 29892015) Colorectal or endometrial cancer ( 26621817) Whole brain grey matter density ( 31530798)
Interacting Genes		11 interacting genes: ADAMTSL4 BMPR1A CAMK2D GMCL1 KRT31 KRT40 REL RYR2 RYR3 TGFBR1 TRIM69	63 interacting genes: APLF APOL6 AXIN1 BYSL C5orf60 CCDC25 CFAP410 CHIC2 CIB3 CLK2 CUL3 ELOA EMD FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL2 GOLGA2 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR NEBL NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 ZNF250
Entrez ID		2281	64395
HPRD ID		02795	13587
Ensembl ID		ENSG00000119782	ENSG00000087338
Uniprot IDs		F8W6G9 P68106	Q53SE7 Q96IK5
PDB IDs		1C9H 4C02 4IQ2 4IQC 5HKG 5L1D 5T15 5T9M 5T9N 5T9R 5T9S 5T9V 5TA3 5TAL 5TAM 5TAN 5TAP 5TAQ 5TAS 5TAT 5TAU 5TAV 5TAW 5TAX 5TAY 5TAZ 5TB0 5TB1 5TB2 5TB3 5TB4 6JI0 6JI8 6JII 6JIU 6JIY 6JRR 6JRS
Enriched GO Terms of Interacting Partners?
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