GMCL1 and TRIM13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GMCL1	TRIM13
Description		germ cell-less 1, spermatogenesis associated	tripartite motif containing 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Matrix	Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Identical Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Multicellular Organism Development Spermatogenesis Cell Differentiation	Anatomical Structure Morphogenesis Response To Gamma Radiation Positive Regulation Of Cell Death Positive Regulation Of Macroautophagy Ubiquitin-dependent ERAD Pathway Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Negative Regulation Of Viral Release From Host Cell Endoplasmic Reticulum Mannose Trimming
Pathways			ER Quality Control Compartment (ERQC)
Drugs			Etorphine Diprenorphine Dihydromorphine
Diseases
GWAS		Atrial fibrillation ( 28416818 30061737 29892015) Colorectal or endometrial cancer ( 26621817) Whole brain grey matter density ( 31530798)	Diastolic blood pressure ( 30224653) Height ( 23563607)
Interacting Genes		63 interacting genes: APLF APOL6 AXIN1 BYSL C5orf60 CCDC25 CFAP410 CHIC2 CIB3 CLK2 CUL3 ELOA EMD FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL2 GOLGA2 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MINDY1 MORF4L1 MPPE1 MTRR NEBL NTAQ1 NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 UBE2I XAGE2 ZNF250	6 interacting genes: AKT1 ARHGDIA GMCL1 MDM2 ROBO2 UBE2D2
Entrez ID		64395	10206
HPRD ID		13587	10414
Ensembl ID		ENSG00000087338	ENSG00000204977
Uniprot IDs		Q53SE7 Q96IK5	A0A024RDU3 L7MTJ6 O60858
PDB IDs
Enriched GO Terms of Interacting Partners?
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