FBN2 and SEMA3F

		FBN2	SEMA3F
Description		fibrillin 2	semaphorin 3F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Microfibril Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix	Extracellular Space Integral Component Of Plasma Membrane Glutamatergic Synapse
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Extracellular Matrix Constituent Conferring Elasticity	Semaphorin Receptor Binding Chemorepellent Activity
	Biological Process	Anatomical Structure Morphogenesis Extracellular Matrix Organization Embryonic Limb Morphogenesis Positive Regulation Of Bone Mineralization Sequestering Of TGFbeta In Extracellular Matrix Camera-type Eye Development Positive Regulation Of Osteoblast Differentiation Embryonic Eye Morphogenesis Bone Trabecula Formation	Neural Crest Cell Migration Axon Guidance Facial Nerve Structural Organization Trigeminal Nerve Structural Organization Nerve Development Branchiomotor Neuron Axon Guidance Positive Regulation Of Cell Migration Ventral Trunk Neural Crest Cell Migration Negative Regulation Of Axon Extension Involved In Axon Guidance Axon Extension Involved In Axon Guidance Negative Chemotaxis Sympathetic Ganglion Development Semaphorin-plexin Signaling Pathway Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Regulation Of Postsynapse Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Semaphorin-plexin Signaling Pathway Involved In Neuron Projection Guidance Semaphorin-plexin Signaling Pathway Involved In Axon Guidance
Pathways		Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs		Calcium Citrate Calcium Phosphate
Diseases		Congenital contractural arachnodactyly (CCA) ; Beals syndrome
GWAS		Atrial fibrillation ( 29892015) Beard thickness ( 26926045) Breastfeeding duration ( 25475840) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Height ( 21998595 31562340) Heschl's gyrus morphology ( 25130324) Intraocular pressure ( 29617998) Medication use (beta blocking agents) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Multiple system atrophy ( 27629089) Night sleep phenotypes ( 27126917) Obesity (extreme) ( 19553259) Pulse pressure ( 27841878 30578418) Response to fenofibrate (total cholesterol levels) ( 27002377) Severe aplastic anemia ( 32004448) Systolic blood pressure ( 28135244 27841878 30578418) Temperament ( 22832960)	Age at first birth ( 27089180) Age at first sexual intercourse ( 27089180) Body mass index ( 26426971 29273807) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Glaucoma ( 31959993) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29785010 31959993) Morning person ( 30696823) Regular attendance at a gym or sports club ( 29970889) Sleep duration (short sleep) ( 30846698)
Interacting Genes		22 interacting genes: CMBL CSF2 DPYSL5 DUSP5 ELN FBN1 FDPS ITGA2 LTBP1 MATN2 MFAP2 MFAP5 NDUFB6 NRG2 RNF14 SEMA3F SIRPA SLC27A6 SMAD2 SNRPB TRIM24 UBE2B	8 interacting genes: FBN2 NRP1 NRP2 SHBG SLC35G2 UBA1 UBC VEGFA
Entrez ID		2201	6405
HPRD ID		00416	03079
Ensembl ID		ENSG00000138829	ENSG00000001617
Uniprot IDs		P35556	C9JPG5 Q13275 Q59G50
PDB IDs
Enriched GO Terms of Interacting Partners?
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