FBN1 and MYOC

  • Number of citations of the paper that reports this interaction (PubMedID 11923248)
  • 52
  • Data Source:
  • HPRD (in vitro)

FBN1

MYOC

Description fibrillin 1 myocilin
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 17903305)
  • Central corneal thickness ( 29760442)
  • Height ( 31562340)
  • Hepcidin/ferritin ratio ( 27846281)
  • Hip circumference adjusted for BMI ( 28552196)
  • Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy) ( 27418160)
  • Intraocular pressure ( 29617998)
  • Macular thickness ( 30535121)
  • Pulse pressure ( 27841878 28739976 30578418)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Systolic blood pressure ( 27841878 30578418)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Thoracic aortic aneurysms and dissections ( 21909107)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Glaucoma ( 30104761)
  • Intake of total sugars ( 31005972)
Interacting Genes 21 interacting genes: ATXN7 CALR CCPG1 DCN ELN FBLN2 FBN2 HSCB HSPG2 LTBP1 MFAP2 MFAP5 MYO5C MYOC PSMC3 RNF111 SECISBP2L SLBP SPRY2 SPTBN5 VCAN 40 interacting genes: A2M ACTA2 ACTB ACTG1 ALDOA ANXA2 C1QB CAP1 CD81 CKM CLIC1 COL1A2 COL3A1 ECE1 EEF1A1 ENO1 FBN1 FN1 FTL FUBP1 GAPDH GGTLC1 HAGH IGLL1 ITGA7 LAMA5 LGALS3 MAEA MYL2 NOTCH2 OLFM3 OLFML3 PKLR PKM RFC1 SERPINF1 TGFBR1 TIMP1 TKT TNFRSF1A
Entrez ID 2200 4653
HPRD ID 00618 03387
Ensembl ID ENSG00000166147 ENSG00000034971
Uniprot IDs P35555 A0A0S2Z421 Q99972
PDB IDs 1APJ 1EMN 1EMO 1LMJ 1UZJ 1UZK 1UZP 1UZQ 2M74 2W86 5MS9 4WXQ 4WXS 4WXU 6OU0 6OU1 6OU2 6OU3 6PKD 6PKE 6PKF
Enriched GO Terms of Interacting Partners?
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