FBLN2 and COL4A5

Number of citations of the paper that reports this interaction (PubMedID 7500359)
30

Data Source:
HPRD (in vivo)

		FBLN2	COL4A5
Description		fibulin 2	collagen type IV alpha 5 chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle	Extracellular Region Collagen Type IV Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction Collagen-containing Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization	Neuromuscular Junction Development Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Pathways		Molecules associated with elastic fibres Molecules associated with elastic fibres	Collagen degradation Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization Regulation of expression of SLITs and ROBOs
Drugs
Diseases			Alport syndrome
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		23 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 ELN FBN1 FN1 HSPG2 ITGB3 LAMA1 LAMA5 LAMC2 MRPS25 NID1 PRELP VCAN ZNF408	19 interacting genes: ANTXR2 ANXA7 APP CD93 CDKN1A DAZAP2 DCN FBLN2 FN1 GLA HABP2 MATN2 MMP9 NR1H2 OSM RNF10 SERPINE2 SMN1 TK1
Entrez ID		2199	1287
HPRD ID		00630	02363
Ensembl ID		ENSG00000163520	ENSG00000188153
Uniprot IDs		P98095 Q86V58 Q9Y3V7	A7MBN3 P29400 Q49AM6
PDB IDs			5NAZ
Enriched GO Terms of Interacting Partners?
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