COL4A5 and FBLN2

Number of citations of the paper that reports this interaction (PubMedID 7500359)
30

Data Source:
HPRD (in vivo)

		COL4A5	FBLN2
Description		collagen type IV alpha 5 chain	fibulin 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction Collagen-containing Extracellular Matrix	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Extracellular Vesicle
	Molecular Function	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength	Extracellular Matrix Structural Constituent Calcium Ion Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Neuromuscular Junction Development Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		Collagen degradation Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization Regulation of expression of SLITs and ROBOs	Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases		Alport syndrome
GWAS			Bipolar disorder with mood-incongruent psychosis ( 23092984) Body mass index ( 26426971) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		19 interacting genes: ANTXR2 ANXA7 APP CD93 CDKN1A DAZAP2 DCN FBLN2 FN1 GLA HABP2 MATN2 MMP9 NR1H2 OSM RNF10 SERPINE2 SMN1 TK1	23 interacting genes: ACAN ATN1 BCAN COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 ELN FBN1 FN1 HSPG2 ITGB3 LAMA1 LAMA5 LAMC2 MRPS25 NID1 PRELP VCAN ZNF408
Entrez ID		1287	2199
HPRD ID		02363	00630
Ensembl ID		ENSG00000188153	ENSG00000163520
Uniprot IDs		A7MBN3 P29400 Q49AM6	P98095 Q86V58 Q9Y3V7
PDB IDs		5NAZ
Enriched GO Terms of Interacting Partners?
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