Description |
coagulation factor II, thrombin |
microtubule associated protein tau |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Lepirudin
- Bivalirudin
- Drotrecogin alfa
- Coagulation Factor IX (Recombinant)
- Menadione
- Argatroban
- Proflavine
- Zinc
- 2-{2-hydroxy-[1,1'-biphenyl]-3-yl}-1H-1,3-benzodiazole-5-carboximidamide
- Beta-(2-Naphthyl)-Alanine
- Hemi-Babim
- 2-(2-Hydroxy-Phenyl)-3h-Benzoimidazole-5-Carboxamidine
- 4-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl)-Piperidin-4-Ylmethyl]-Amide
- 4-Iodobenzo[B]Thiophene-2-Carboxamidine
- CRA_8696
- Gamma-Carboxy-Glutamic Acid
- 6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine
- Lysophosphotidylserine
- N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN-4-AMINE
- TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE
- 2-(3-CHLORO-6-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-1-OXIDOPYRIDIN-2-YL)-N-[1-(3-CHLOROPHENYL)ETHYL]ACETAMIDE
- 1-GUANIDINO-4-(N-NITRO-BENZOYLAMINO-L-LEUCYL-L-PROLYLAMINO)BUTANE
- 1-GUANIDINO-4-(N-PHENYLMETHANESULFONYL-L-LEUCYL-L-PROLYLAMINO)BUTANE
- Suramin
- Ximelagatran
- Thrombomodulin Alfa
- Human C1-esterase inhibitor
- Dabigatran etexilate
- methyl L-phenylalaninate
- D-phenylalanyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl)butyl]-L-prolinamide
- (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide
- (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide
- N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
- N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
- N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE
- 6-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINE
- 6-CARBAMIMIDOYL-2-[2-HYDROXY-6-(4-HYDROXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID
- 6-CARBAMIMIDOYL-2-[2-HYDROXY-5-(3-METHOXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID
- N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide
- 1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE
- 1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide
- D-leucyl-N-(3-chlorobenzyl)-L-prolinamide
- D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide
- 1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
- N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamide
- N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide
- 1-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamide
- D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
- D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide
- (3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinoline
- D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide
- beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamide
- (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide
- (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamide
- (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide
- 2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE
- N4-(N,N-DIPHENYLCARBAMOYL)-AMINOGUANIDINE
- N7-BUTYL-N2-(5-CHLORO-2-METHYLPHENYL)-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2,7-DIAMINE
- (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamide
- D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide
- D-phenylalanyl-N-benzyl-L-prolinamide
- N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDE
- 3-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamide
- (2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE
- 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE
- 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHENESULFONAMIDE
- N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDE
- 4-(2,5-DIAMINO-5-HYDROXY-PENTYL)-PHENOL
- 2-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER
- 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)
- 1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE
- 4-TERT-BUTYLBENZENESULFONIC ACID
- 3-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE
- 4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE
- 1-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL
- 6-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL
- N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDE
- N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDE
- 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDE
- 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-3-METHYL-6-PYRIDINYL)METHYL]ACETAMIDE
- 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDO-2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUOROPHENYL)METHYL]ACETAMIDE
- 3-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTER
- AC-(D)PHE-PRO-BOROLYS-OH
- AC-(D)PHE-PRO-BOROHOMOLYS-OH
- AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH
- N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamide
- 3-(4-HYDROXY-PHENYL)PYRUVIC ACID
- 4-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINE
- (3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINE
- HYL)BENZENECARBOXIMIDAMIDE
- 1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE
- [[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE
- N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE
- N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamide
- 4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE
- 3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE
- {(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate
- METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINE
- 2-NAPHTHALENESULFONIC ACID
- [PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINE
- 4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDE
- BENZOTHIAZOLE
- Copper
- Conestat alfa
- Antithrombin Alfa
- Nafamostat
- Gabexate
- Anti-inhibitor coagulant complex
- Coagulation Factor IX Human
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Diseases |
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GWAS |
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Interacting Genes |
41 interacting genes:
AANAT
AKR7A2
AMBP
C6
CPB2
DDIT3
F11
F13A1
F2R
F2RL1
F2RL2
F2RL3
F5
F8
F9
FGA
GGCX
GP1BA
GP5
HGFAC
IGFBP3
IGFBP5
ITGA2B
KNG1
MAPT
PLAU
PROC
PROS1
PROZ
SERPINA5
SERPINB6
SERPINB8
SERPINC1
SERPIND1
SERPINE1
SERPINE2
SERPING1
SPP1
ST13
THBD
THBS1
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128 interacting genes:
AATF
ABL1
ACTA1
ACTB
ACTG1
AKT1
AMPH
APOE
APP
ARHGEF40
BAG1
BRSK1
BRSK2
CALM1
CAMK2A
CAPN1
CAPN2
CASP1
CASP3
CASP6
CASP7
CASP8
CDK1
CDK2
CDK5
CHEK1
CHEK2
CREBBP
CSNK1A1
CSNK1D
CSNK2A1
CTSD
DUSP1
DYRK1A
DYRK2
EGFR
EP300
F2
FKBP1A
FKBP5
FYN
GRB2
GSK3A
GSK3B
HDAC6
HOOK3
HSP90AA1
HSPA8
HSPB1
HTRA1
LCK
LGMN
LRRK2
MAP2K7
MAPK1
MAPK10
MAPK11
MAPK12
MAPK13
MAPK14
MAPK3
MAPK8
MAPK9
MARCHF7
MARK1
MARK2
MARK3
MARK4
MASP1
MELK
NPEPPS
OGT
OTUB1
PACSIN1
PDIA2
PEG10
PHKG1
PIK3R1
PIN1
PKN1
PLCG1
PPP1CA
PPP1CB
PPP1CC
PPP2CA
PPP2CB
PPP2R5A
PPP5C
PRKACA
PRKCA
PRKCB
PRKCD
PRKCE
PRKCG
PRKCI
PRKCZ
PSEN1
PTK2B
PTPA
PWP2
RPS6KA1
RPS6KA3
RPS6KA5
RPS6KB1
S100B
SIK1
SIRT1
SNCA
SPTB
SQSTM1
SRC
SRPK1
SRPK2
STAU1
STUB1
STXBP1
SYK
TRAF6
TTBK1
TUBA1B
TUBA4A
TUBB
TUBB3
UBB
UBE2D2
USP9Y
YWHAB
YWHAZ
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Entrez ID |
2147 |
4137 |
HPRD ID |
01488 |
01142 |
Ensembl ID |
ENSG00000180210
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ENSG00000186868
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Uniprot IDs |
P00734
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A0A024R9Y0
A0A024R9Y1
A0A024RA17
A0A024RA19
B3KTM0
P10636
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PDB IDs |
1A2C
1A3B
1A3E
1A46
1A4W
1A5G
1A61
1ABI
1ABJ
1AD8
1AE8
1AFE
1AHT
1AI8
1AIX
1AWF
1AWH
1AY6
1B5G
1B7X
1BA8
1BB0
1BCU
1BHX
1BMM
1BMN
1BTH
1C1U
1C1V
1C1W
1C4U
1C4V
1C4Y
1C5L
1C5N
1C5O
1CA8
1D3D
1D3P
1D3Q
1D3T
1D4P
1D6W
1D9I
1DE7
1DIT
1DM4
1DOJ
1DWB
1DWC
1DWD
1DWE
1DX5
1E0F
1EB1
1EOJ
1EOL
1FPC
1FPH
1G30
1G32
1G37
1GHV
1GHW
1GHX
1GHY
1GJ4
1GJ5
1H8D
1H8I
1HAG
1HAH
1HAI
1HAO
1HAP
1HBT
1HDT
1HGT
1HLT
1HUT
1HXE
1HXF
1IHS
1IHT
1JMO
1JOU
1JWT
1K21
1K22
1KTS
1KTT
1LHC
1LHD
1LHE
1LHF
1LHG
1MH0
1MU6
1MU8
1MUE
1NM6
1NO9
1NRN
1NRO
1NRP
1NRQ
1NRR
1NRS
1NT1
1NU7
1NU9
1NY2
1NZQ
1O0D
1O2G
1O5G
1OOK
1OYT
1P8V
1PPB
1QBV
1QHR
1QJ1
1QJ6
1QJ7
1QUR
1RD3
1RIW
1SB1
1SFQ
1SG8
1SGI
1SHH
1SL3
1SR5
1T4U
1T4V
1TA2
1TA6
1TB6
1TBZ
1THP
1THR
1THS
1TMB
1TMT
1TMU
1TOM
1TQ0
1TQ7
1TWX
1UMA
1UVS
1VR1
1VZQ
1W7G
1WAY
1WBG
1XM1
1XMN
1YPE
1YPG
1YPJ
1YPK
1YPL
1YPM
1Z71
1Z8I
1Z8J
1ZGI
1ZGV
1ZRB
2A0Q
2A2X
2A45
2AFQ
2ANK
2ANM
2B5T
2BDY
2BVR
2BVS
2BVX
2BXT
2BXU
2C8W
2C8X
2C8Y
2C8Z
2C90
2C93
2CF8
2CF9
2CN0
2FEQ
2FES
2GDE
2GP9
2H9T
2HGT
2HNT
2HPP
2HPQ
2HWL
2JH0
2JH5
2JH6
2OD3
2PGB
2PGQ
2PKS
2PW8
2R2M
2THF
2UUF
2UUJ
2UUK
2V3H
2V3O
2ZC9
2ZDA
2ZDV
2ZF0
2ZFF
2ZFP
2ZFQ
2ZFR
2ZG0
2ZGB
2ZGX
2ZHE
2ZHF
2ZHQ
2ZHW
2ZI2
2ZIQ
2ZNK
2ZO3
3B23
3B9F
3BEF
3BEI
3BF6
3BIU
3BIV
3BV9
3C1K
3C27
3D49
3DA9
3DD2
3DHK
3DT0
3DUX
3E6P
3EE0
3EGK
3EQ0
3F68
3GIC
3GIS
3HAT
3HKJ
3HTC
3JZ1
3JZ2
3K65
3LDX
3LU9
3NXP
3P17
3P6Z
3P70
3PMH
3PO1
3QDZ
3QGN
3QLP
3QTO
3QTV
3QWC
3QX5
3R3G
3RLW
3RLY
3RM0
3RM2
3RML
3RMM
3RMN
3RMO
3S7H
3S7K
3SHA
3SHC
3SI3
3SI4
3SQE
3SQH
3SV2
3T5F
3TU7
3U69
3U8O
3U8R
3U8T
3U98
3U9A
3UTU
3UWJ
3VXE
3VXF
4AX9
4AYV
4AYY
4AZ2
4BAH
4BAK
4BAM
4BAN
4BAO
4BAQ
4BOH
4CH2
4CH8
4DIH
4DII
4DT7
4DY7
4E05
4E06
4E7R
4H6S
4H6T
4HFP
4HTC
4HZH
4I7Y
4LOY
4LXB
4LZ1
4LZ4
4MLF
4NZQ
4O03
4RKJ
4RKO
4RN6
4THN
4UD9
4UDW
4UE7
4UEH
4UFD
4UFE
4UFF
4UFG
4YES
5A2M
5AF9
5AFY
5AFZ
5AHG
5CMX
5DO4
5E8E
5EDK
5EDM
5EW1
5EW2
5GDS
5GIM
5JDU
5JFD
5JZY
5L6N
5MJT
5MLS
5MM6
5NHU
5TO3
5Z5W
5Z5X
6BJR
6C2W
6EO6
6EO7
6EO8
6EO9
7KME
8KME
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1I8H
2MZ7
2ON9
3OVL
4E0M
4E0N
4E0O
4FL5
4GLR
4NP8
4TQE
4Y32
4Y3B
4Y5I
5DMG
5E2V
5E2W
5HF3
5K7N
5MO3
5MP1
5MP3
5MP5
5N5A
5N5B
5NVB
5O3L
5O3O
5O3T
5V5B
5V5C
5ZIA
5ZV3
6BB4
6CVJ
6CVN
6DC8
6DC9
6DCA
6FBW
6FI5
6GK7
6GK8
6GX5
6H06
6HRE
6HRF
6N4P
6NWP
6NWQ
6ODG
6QJH
6QJM
6QJP
6QJQ
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Enriched GO Terms of Interacting Partners? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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