EYA1 and H2AX

  • Number of citations of the paper that reports this interaction (PubMedID 19234442)
  • 199
  • Data Source:
  • BioGRID (enzymatic study, affinity chromatography technology)

EYA1

H2AX

Description EYA transcriptional coactivator and phosphatase 1 H2A.X variant histone
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adolescent idiopathic scoliosis ( 30395268)
  • Chin dimples ( 27182965)
  • Chronic obstructive pulmonary disease-related biomarkers ( 23144326)
  • Heel bone mineral density ( 30598549 28869591)
  • Hypospadias ( 25108383)
  • Longevity (85 years and older) ( 24688116)
  • Paneth cell defects in Crohn's disease ( 28352666)
  • Sleep-related phenotypes ( 17903308)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 9 interacting genes: DACH1 GNAI2 GNAZ GSK3B H2AX NDUFB9 SIX1 SIX2 SIX3 47 interacting genes: A2M ACTB ALG9 ATM ATR BARD1 BMI1 BRCA1 BRCA2 BRD1 CALM1 COPG1 DDX21 DHX9 EYA1 HUWE1 KAT5 MASP1 MDC1 MRE11 NBN NCL NGFR OTUB1 PAXIP1 PBK PPP1CA PRKDC PTPA QARS1 RNF168 RNF8 RPS6KA3 SMARCA4 SSRP1 SUPT16H SUPT5H TAF1C TAF5L TERF2 TIAM2 TOPORS TP53BP1 TRAF6 TSSK6 USP11 WRN
Entrez ID 2138 3014
HPRD ID 03388 03465
Ensembl ID ENSG00000104313 ENSG00000188486
Uniprot IDs A0A024R813 A0A2R8Y6K4 A6NCB9 B3KXR1 F8WB53 Q0P517 Q99502 P16104
PDB IDs 1YDP 2AZM 2D31 2DYP 3SHV 3SQD 3SZM 3U3Z
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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