ERG and PCBP1

Number of citations of the paper that reports this interaction (PubMedID 21575865)
167

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		ERG	PCBP1
Description		ETS transcription factor ERG	poly(rC) binding protein 1
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm Ribonucleoprotein Complex	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Signal Transduction Multicellular Organism Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II
Pathways			mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases		Ewing's sarcoma Prostate cancer
GWAS		Abdominal aortic aneurysm ( 27899403) Amyotrophic lateral sclerosis (sporadic) ( 24529757) B-cell acute lymphoblastic leukaemia ( 31767839) B-cell acute lymphoblastic leukaemia (high-hyperdiploidy) ( 31767839) Diastolic blood pressure ( 27841878 30578418) General cognitive ability ( 25383866) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549 28869591) Iron status biomarkers (iron levels) ( 28334935) Keratinocyte cancer (MTAG) ( 31174203) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Metabolite levels (HVA) ( 23319000) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244 27386562) Neonatal lupus ( 20662065) Non-response to antidepressants and depression ( 27622933) Platelet count ( 27863252) Plateletcrit ( 27863252) Pulse pressure ( 27841878 30578418) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)	Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)
Interacting Genes		73 interacting genes: ACTB ADAR APP CDC5L CLTC DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 FBL FLI1 HERC2 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 HUWE1 ILF2 ILF3 JUN LANCL1 MATR3 NCL NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 POLR2A PRKDC PRPF40A PRPF8 PUF60 RCC2 RING1 RNF2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SNRNP200 SPI1 SPOP STUB1 SYN1 TOP1 TOP2B TRIM25 TRIM33 TRIP12 UBR4 UBR5 UHRF1 USP9X XRN2	42 interacting genes: ANP32A APP CAV3 CELF2 CELF3 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL LMNA MATR3 MOGS NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM42 SNRPA SRPK2 SRSF3 TCERG1 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830
Entrez ID		2078	5093
HPRD ID		01298	03128
Ensembl ID		ENSG00000157554	ENSG00000169564
Uniprot IDs		A0A0C4DG41 B4DN83 B4DVX5 B5MDW0 P11308	Q15365 Q53SS8
PDB IDs		1SXE 4IRG 4IRH 4IRI 5YBC 5YBD	1WVN 1ZTG 3VKE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?