EIF1AX and EIF5B

Number of citations of the paper that reports this interaction (PubMedID 12514125)
62

		EIF1AX	EIF5B
Description		eukaryotic translation initiation factor 1A X-linked	eukaryotic translation initiation factor 5B
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding	RNA Binding Translation Initiation Factor Activity GTPase Activity Protein Binding GTP Binding Metal Ion Binding
	Biological Process	Translational Initiation	Translational Initiation Regulation Of Translational Initiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Interacting Genes		8 interacting genes: APP EIF2S1 EIF3C EIF5 EIF5B HSPB1 IKBKG IPO13	10 interacting genes: BRCA1 CBL CSNK2A1 ECT2 EIF1AX ETS1 PAXIP1 SIRPA TFCP2 ZBTB3
Entrez ID		1964	9669
HPRD ID		02174	07304
Ensembl ID		ENSG00000173674	ENSG00000158417
Uniprot IDs		P47813	O60841 Q8N5A0
PDB IDs		1D7Q 3ZJY 4KZY 4KZZ
Enriched GO Terms of Interacting Partners?
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