DRD5 and GNAZ

Number of citations of the paper that reports this interaction (PubMedID 9603210)
16

Data Source:
HPRD (in vitro, in vivo)

		DRD5	GNAZ
Description		dopamine receptor D5	G protein subunit alpha z
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Cilium Brush Border Membrane Synapse Ciliary Membrane Non-motile Cilium	Nuclear Envelope Endoplasmic Reticulum Cytosol Heterotrimeric G-protein Complex Plasma Membrane Dendrite Cell Body
	Molecular Function	Dopamine Neurotransmitter Receptor Activity, Coupled Via Gs Adrenergic Receptor Activity Dopamine Neurotransmitter Receptor Activity Dopamine Binding	G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Binding Metal Ion Binding
	Biological Process	Synaptic Transmission, Dopaminergic Response To Amphetamine Regulation Of Systemic Arterial Blood Pressure By Vasopressin Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Cellular Calcium Ion Homeostasis G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Behavior Associative Learning Transmission Of Nerve Impulse Negative Regulation Of NAD(P)H Oxidase Activity Wound Healing Response To Cocaine Positive Regulation Of Adenylate Cyclase Activity Negative Regulation Of Blood Pressure Regulation Of Female Receptivity Sensitization Phospholipase C-activating Dopamine Receptor Signaling Pathway Long-term Synaptic Depression Cellular Response To Catecholamine Stimulus Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Reactive Oxygen Species Metabolic Process	Protein Folding G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Pathways		Dopamine receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	PLC beta mediated events PLC beta mediated events G-protein activation G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding ADORA2B mediated anti-inflammatory cytokines production
Drugs		Ziprasidone Cabergoline Cabergoline Ropinirole Olanzapine Olanzapine Mirtazapine Loxapine Loxapine Pramipexole Imipramine Chlorpromazine Chlorpromazine Cinnarizine Lisuride Ergotamine Apomorphine Trimipramine Fenoldopam Dopamine Dopamine Carphenazine Pergolide Bromocriptine Quetiapine Levodopa Aripiprazole Methotrimeprazine Zuclopenthixol Rotigotine Mianserin Quinagolide
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Impulsivity (motor) ( 30718321) Lung cancer ( 28604730) Manganese levels ( 26025379) Metabolite levels ( 23823483)	Handedness (Left-handed vs. non-left-handed) ( 31504236) Handedness (left-handed vs. right-handed) ( 31504236) Height ( 18391951)
Interacting Genes		5 interacting genes: GABRG2 GNA12 GNA13 GNAZ NCS1	16 interacting genes: ADORA1 APP DRD2 DRD5 EYA1 EYA2 LRRK1 NMT1 NUCB1 OPRD1 PRKCD RAP1GAP RGS10 RGS19 RGS20 RGS7
Entrez ID		1816	2781
HPRD ID		00542	00746
Ensembl ID		ENSG00000169676	ENSG00000128266
Uniprot IDs		P21918	P19086 Q8IY73
PDB IDs
Enriched GO Terms of Interacting Partners?
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