DMPK and CELF1

Number of citations of the paper that reports this interaction (PubMedID 9371827)
48

Data Source:
HPRD (in vitro)

		DMPK	CELF1
Description		DM1 protein kinase	CUGBP Elav-like family member 1
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GO Annotations	Cellular Component	Cell Nuclear Outer Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Mitochondrial Outer Membrane Nuclear Membrane Sarcoplasmic Reticulum Membrane	Nucleus Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Myosin Phosphatase Regulator Activity Metal Ion Binding	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding BRE Binding
	Biological Process	Regulation Of Sodium Ion Transport Protein Phosphorylation Cellular Calcium Ion Homeostasis Nuclear Envelope Organization Regulation Of Heart Contraction Muscle Cell Apoptotic Process Regulation Of Myotube Differentiation Regulation Of Skeletal Muscle Contraction By Calcium Ion Signaling Regulation Of Excitatory Postsynaptic Membrane Potential Involved In Skeletal Muscle Contraction Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Synapse Structural Plasticity Regulation Of Cardiac Conduction	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Germ Cell Development Embryo Development Ending In Birth Or Egg Hatching RNA Interference Negative Regulation Of Translation Regulation Of RNA Splicing
Pathways		Ion homeostasis
Drugs		3-[1-(3-Aminopropyl)-1h-Indol-3-Yl]-4-(1-Methyl-1h-Indol-3-Yl)-1h-Pyrrole-2,5-Dione
Diseases		Myotonic dystrophy (DM)
GWAS		Chronic obstructive pulmonary disease or coronary artery disease (pleiotropy) ( 30940143)	Alcohol use disorder (total score) ( 30336701) Alzheimer's disease ( 31473137) Alzheimer's disease (late onset) ( 24162737) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body mass index ( 28552196) Estimated glomerular filtration rate ( 30604766) Global electrical heterogeneity phenotypes ( 29622589) Glomerular filtration rate ( 29403010) Hand grip strength ( 29691431) Immature fraction of reticulocytes ( 27863252) Loneliness ( 31518406 29970889) Loneliness (MTAG) ( 29970889) Metabolic syndrome ( 31589552) Neuroticism ( 29255261) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Sleep duration (short sleep) ( 30846698) Total cholesterol levels ( 30275531) Type 2 diabetes ( 30297969)
Interacting Genes		19 interacting genes: ANXA7 ATN1 ATXN1 CELF1 FXYD1 GABARAP GEMIN4 HOXA2 HSPB2 PIN1 PLN PPP1R12A PVR RAC1 RAF1 RPS10 SMN1 TK1 UBQLN4	7 interacting genes: APP DMPK FUBP1 HNRNPC PPBP RALY TOM1L1
Entrez ID		1760	10658
HPRD ID		05645	03046
Ensembl ID		ENSG00000104936	ENSG00000149187
Uniprot IDs		B4DM55 B4DZE2 E5KR05 E5KR06 E5KR07 I6L989 Q09013	G5EA30 Q92879
PDB IDs		1WT6 2VD5	2CPZ 2DHS 2RQ4 2RQC 3NMR 3NNA 3NNC 3NNH
Enriched GO Terms of Interacting Partners?
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