AFP and AP4S1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

		AFP	AP4S1
Description		alpha fetoprotein	adaptor related protein complex 4 subunit sigma 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endoplasmic Reticulum Lumen	AP-4 Adaptor Complex Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Fatty Acid Binding Protein Binding Zinc Ion Binding
	Biological Process	Ovulation From Ovarian Follicle Transport Progesterone Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process SMAD Protein Signal Transduction	Protein Targeting Protein Localization Vesicle-mediated Transport
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Lysosome Vesicle Biogenesis
Drugs
Diseases			Cerebral palsy
GWAS		Blood protein levels ( 30072576) Prostate cancer ( 23535732) Tumor biomarkers ( 23300138)
Interacting Genes		10 interacting genes: AP4S1 CCR5 EHD4 GNB1 MED27 PHB2 PIDD1 PSMB7 SGSM2 XIAP	5 interacting genes: AFP APP GRB2 GTF2I TEAD3
Entrez ID		174	11154
HPRD ID		00074	06257
Ensembl ID		ENSG00000081051	ENSG00000100478
Uniprot IDs		P02771	Q9Y587
PDB IDs		3MRK
Enriched GO Terms of Interacting Partners?
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