DHPS and PTPRH

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		DHPS	PTPRH
Description		deoxyhypusine synthase	protein tyrosine phosphatase receptor type H
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Integral Component Of Plasma Membrane Apical Plasma Membrane Microvillus Membrane
	Molecular Function	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Cadherin Binding
	Biological Process	Translation Spermidine Metabolic Process Positive Regulation Of Cell Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine	Protein Dephosphorylation Apoptotic Process Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity
Pathways		Hypusine synthesis from eIF5A-lysine
Drugs		1-Guanidinium-7-Aminoheptane
Diseases
GWAS			Plateletcrit ( 27863252) Systemic lupus erythematosus ( 28714469)
Interacting Genes		13 interacting genes: BRCA1 EIF5A EIF5A2 NIF3L1 NTAQ1 NUDT18 PTPRH RAB27B REL RPL9 UPF1 VASH1 ZNF138	15 interacting genes: BCAR1 CRK DHPS DOK1 EGFR ERBB3 ERBB4 GHR KRTAP10-3 KRTAP10-8 LCK MAPK1 MLH1 PTK2 PXN
Entrez ID		1725	5794
HPRD ID		02969	03942
Ensembl ID		ENSG00000095059	ENSG00000080031
Uniprot IDs		A0A024R7D0 A0A024R7E9 P49366	Q9HD43
PDB IDs		1DHS 1RLZ 1ROZ 1RQD
Enriched GO Terms of Interacting Partners?
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