DCX and USP9X

Number of citations of the paper that reports this interaction (PubMedID 15607950)
19

Data Source:
HPRD (in vivo, two hybrid)

		DCX	USP9X
Description		doublecortin	ubiquitin specific peptidase 9 X-linked
Image
GO Annotations	Cellular Component	Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Axoneme Neuron Projection	Cytoplasm Cytosol Membrane Growth Cone
	Molecular Function	Protein Binding Microtubule Binding Protein Kinase Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Thiol-dependent Ubiquitinyl Hydrolase Activity Co-SMAD Binding Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Neuron Migration Nervous System Development Central Nervous System Development Axoneme Assembly Intracellular Signal Transduction Photoreceptor Cell Development Retina Development In Camera-type Eye	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Protein Targeting To Peroxisome Cell Cycle Chromosome Segregation Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Cell Migration Protein Ubiquitination Protein Deubiquitination BMP Signaling Pathway Regulation Of Circadian Rhythm Cellular Protein Metabolic Process Rhythmic Process Axon Extension Protein Stabilization Cell Division Protein K48-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Demethylation
Pathways		Neurofascin interactions	Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Peroxisomal protein import Peroxisomal protein import Amyloid fiber formation
Drugs
Diseases		Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS			Migraine ( 27322543)
Interacting Genes		30 interacting genes: ACD AP1M1 AP2M1 APP CALCOCO2 CDK5 FBXO25 GOLGA2 IKZF1 KIFC3 KRT40 KRTAP10-8 MEOX1 MID2 NFASC PAFAH1B1 POT1 PPP1CA PPP1R9B RBM5 RINT1 SPAG5 SPP1 TERF1 TINF2 TRIM23 TRIM27 TRIM39 USP9X ZBTB5	21 interacting genes: AFDN ALDH1A3 BCL9 CTNNB1 DCX ERG FBXW7 GPSM1 MAP3K5 MCL1 PEX5 PSD4 RNF115 SMAD2 SMAD4 SMN2 SMURF1 STIL TDRD3 UBC VHL
Entrez ID		1641	8239
HPRD ID		02127	02091
Ensembl ID		ENSG00000077279	ENSG00000124486
Uniprot IDs		A8K340 O43602	Q6P468 Q86X58 Q93008
PDB IDs		1MJD 2BQQ 2XRP 4ATU 5IKC 5IN7 5IO9 5IOI 5IP4 6FNZ	5VBD 5WCH
Enriched GO Terms of Interacting Partners?
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