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USP9X
Description
ubiquitin specific peptidase 9 X-linked
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Membrane
Growth Cone
Molecular Function
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cysteine-type Peptidase Activity
Thiol-dependent Ubiquitinyl Hydrolase Activity
Co-SMAD Binding
Ubiquitinyl Hydrolase Activity
Lys48-specific Deubiquitinase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Neuron Migration
Protein Targeting To Peroxisome
Cell Cycle
Chromosome Segregation
Transforming Growth Factor Beta Receptor Signaling Pathway
Female Gamete Generation
Cell Migration
Protein Ubiquitination
Protein Deubiquitination
BMP Signaling Pathway
Regulation Of Circadian Rhythm
Cellular Protein Metabolic Process
Rhythmic Process
Axon Extension
Protein Stabilization
Cell Division
Protein K48-linked Deubiquitination
Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of DNA Demethylation
Pathways
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Ub-specific processing proteases
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Peroxisomal protein import
Peroxisomal protein import
Amyloid fiber formation
Drugs
Diseases
GWAS
Migraine (
27322543
)
Interacting Genes
21 interacting genes:
AFDN
ALDH1A3
BCL9
CTNNB1
DCX
ERG
FBXW7
GPSM1
MAP3K5
MCL1
PEX5
PSD4
RNF115
SMAD2
SMAD4
SMN2
SMURF1
STIL
TDRD3
UBC
VHL
Entrez ID
8239
HPRD ID
02091
Ensembl ID
ENSG00000124486
Uniprot IDs
Q6P468
Q86X58
Q93008
PDB IDs
5VBD
5WCH
Enriched GO Terms of Interacting Partners
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