IFNLR1 and IFNL2

Number of citations of the paper that reports this interaction (PubMedID 12469119)
445

Data Source:
HPRD (in vivo)

		IFNLR1	IFNL2
Description		interferon lambda receptor 1	interferon lambda 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Receptor Activity Protein Binding	Signaling Receptor Binding Cytokine Activity
	Biological Process	Mucosal Immune Response Negative Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Response To Type III Interferon Regulation Of Defense Response To Virus By Host Defense Response To Virus	Mucosal Immune Response JAK-STAT Cascade Cytokine-mediated Signaling Pathway Innate Immune Response Positive Regulation Of Immune Response Defense Response To Virus
Pathways		Other interleukin signaling Interleukin-20 family signaling	Interleukin-20 family signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Inflammatory skin disease ( 25574825) Molybdenum levels ( 26025379) Psoriasis vulgaris ( 26626624)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
Interacting Genes		3 interacting genes: IFNL1 IFNL2 LSM8	2 interacting genes: IFNLR1 IL10RB
Entrez ID		163702	282616
HPRD ID		09589	09586
Ensembl ID		ENSG00000185436	ENSG00000183709
Uniprot IDs		Q8IU57	Q8IZJ0
PDB IDs		3OG4 3OG6 5IXD 5IXI 5L04 5T5W
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?